DOI QR코드

DOI QR Code

The Effect of Probiotics on Microbiology, Health and Performance of Fattening Rabbits

  • Kritas, S.K. (Department of Microbiology and Infectious Diseases, School of Veterinary Medicine Aristotle University of Thessaloniki) ;
  • Petridou, E.I. (Department of Microbiology and Infectious Diseases, School of Veterinary Medicine Aristotle University of Thessaloniki) ;
  • Fortomaris, P. (Department of Animal Husbandry, School of Veterinary Medicine, Aristotle University of Thessaloniki) ;
  • Tzika, E. (Clinic of Production Animal Medicine, School of Veterinary Medicine, Aristotle University of Thessaloniki) ;
  • Arsenos, G. (Department of Animal Husbandry, School of Veterinary Medicine, Aristotle University of Thessaloniki) ;
  • Koptopoulos, G. (Department of Microbiology and Infectious Diseases, School of Veterinary Medicine Aristotle University of Thessaloniki)
  • Received : 2007.03.31
  • Accepted : 2007.12.02
  • Published : 2008.09.01

Abstract

The objective of the present trial was to determine the effect of a thermostable probiotic containing Bacillus licheniformis and B. subtilis on health and production parameters of fattening rabbits from weaning until slaughter. In a rabbitry with average post-weaning mortality of 5-9%, 1,680 rabbits were supplied with: a) a basic feed, or b) the same basic feed supplemented with probiotic from the 4th day postweaning (41st day of age) up to 88th day of age. Clinical signs, microbiological status and growth performance were recorded for two distinct fattening periods, growing and finishing. A significant decrease in mortality of probiotic-treated rabbits when compared to the controls was observed during the growing and entire fattening periods. Within these periods, E. coli and C. perfringens - but not P. multocida - were isolated at a lower frequency from probiotic-treated rabbits (p<0.05). Compared to the control animals, probiotic-treated rabbits were 54 g and 123 g heavier at the end of the growing and finishing phases, respectively, and had significantly higher average daily gain and better feed conversion ratio (p<0.05).

Keywords

References

  1. Abe, F., N. Ishibashi and S. Shimamura. 1995. Effect of administration of bifidobacteria and lactic acid bacteria to newborn calves and piglets. J. Dairy Sci. 78(12):2838-2846. https://doi.org/10.3168/jds.S0022-0302(95)76914-4
  2. Alvarez, S., C. Herrero, E. Bru and G. Perdigon. 2001. Effect of Lactobacillus casei and yogurt administration on prevention of Pseudomonas aeruginosa infection in young mice. J. Food Protect. 64(11): 1768-1774. https://doi.org/10.4315/0362-028X-64.11.1768
  3. Bengmark, S. 2005. Synbiotics and the mucosal barrier in critically ill patients. Curro Opin. Gastroenter. 21(6):712-716. https://doi.org/10.1097/01.mog.0000182858.65927.81
  4. Berge, A. C., P. Lindeque, D. A. Moore and W. M. Sischo. 2005. A clinical trial evaluating prophylactic and therapeutic antibiotic use on health and performance of preweaned calves. J. Dairy Sci. 88(6):2166-2177. https://doi.org/10.3168/jds.S0022-0302(05)72892-7
  5. Buttery, P. 1993. Growth promotion in animals -an overview. In: Livestock productivity enchancers: An economic assessment. CAB International, UK. pp. 7-23.
  6. Collado, M. C., M. Gueimonde, Y. Sanz and S. Salminen. 2006. Adhesion properties and competitive pathogen exclusion ability of bifidobacteria with acquired acid resistance. J. Food Protect. 69(7):1675-1679. https://doi.org/10.4315/0362-028X-69.7.1675
  7. Cross, M. L. 2002. Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens. FEMS Immun. Med. Microbiol. 13; 34(4):245-253. https://doi.org/10.1111/j.1574-695X.2002.tb00632.x
  8. Fortun-Lamothe, L. and S. Boullier. 2007. A review on the interactions between gut micro flora and digestive mucosal immunity. Possible ways to improve the health of rabbits. Livestock Sci. 107:1-18. https://doi.org/10.1016/j.livsci.2006.09.005
  9. Fuller, R. 1989. Probiotics in man and animals. J. Appl. Bacteriol. 66:365-368. https://doi.org/10.1111/j.1365-2672.1989.tb05105.x
  10. Fuller, R. 1991. Probiotics in human medicine. Gut 32(4):439-442. https://doi.org/10.1136/gut.32.4.439
  11. Hara-Kudo, Y., Y. Morishita, Y. Nagaoka, F. Kasuga and S. Kumagai. 1996. Incidence of diarrhea with antibiotics and the increase of clostridia in rabbits. J. Vet. Med. Sci. 58(12): 1181-1185. https://doi.org/10.1292/jvms.58.12_1181
  12. Kanitz, E., M. Tuchscherer, B. Puppe, A. Tuchscherer and B. Stabenow. 2004. Consequences of repeated early isolation in domestic piglets (Sus scrofa) on their behavioural, neuroendocrine, and immunological responses. Brain Behav. Immun. 18(1):35-45. https://doi.org/10.1016/S0889-1591(03)00085-0
  13. Kizerwetter-Swida, M. and M. Binek. 2005. Selection of potentially probiotic Lactobacillus strain towards their inhibitory activity against poultry enteropathogenic bacteria. Polish J. Microbiol. 54(4):287-294.
  14. Kritas, S. K. and R. B. Morrison. 2005. Evaluation ofprobiotics as a substitute for antibiotics in a large pig nursery. Vet. Rec. 2; 156(14):447-448. https://doi.org/10.1136/vr.156.14.447
  15. Kritas, S. K. and R. B. Morrison. 2007. Effect of orally administered Lactobacillus casei on porcine reproductive and respiratory syndrome (PRRS) virus vaccination in pigs. Vet. Microbiol. 119:248-255. https://doi.org/10.1016/j.vetmic.2006.09.012
  16. Kustos, K., D. Kovacs, K. Godor-Surmarm and C. S. Eiben. 2004. Effect of probiotic Bioplus 2B on performance of growing rabbit. Proc. 8th World Rabbit Congress. Universidade De Puebla, Puebla, Mexico. 874-879.
  17. Kyriakis, S. C., K. Sarris, S. K. Kritas, A. C. Tsinas and C. Giannakopoulos. 1996. Effect of salinomycin in the control of Clostridium perfringens type C infections in sucklings pigs. Vet. Rec. 23; 138(12):281-283.
  18. Lee, D. J., R. A. Drongowski, A. G. Coran and C. M. Harmon. 2000. Evaluation of probiotic treatment in a neonatal animal model. Ped. Surg. Internat. 16(4):237-242. https://doi.org/10.1007/s003830050736
  19. Mattar, A. F., R. A. Drongowski, A. G. Coran and C. M. Harmon. 2001. Effect of probiotics on enterocyte bacterial translocation in vitro. Ped. Surg. Internat. 17(4):265-268. https://doi.org/10.1007/s003830100591
  20. McFarland, L. V. 2006. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am. J. Gastroenterol. 101(4):812-822. https://doi.org/10.1111/j.1572-0241.2006.00465.x
  21. Morrow-Tesch, J. and G. Andersson. 1994. Immnnological and hematological characterizations of the wasting pig syndrome. J. Anim. Sci. 72(4):976-983. https://doi.org/10.2527/1994.724976x
  22. O'Hara, A. M. and F. Shanahan. 2006. The gut flora as a forgotten organ. EMBO Reports 7(7):688-693. https://doi.org/10.1038/sj.embor.7400731
  23. O'Hara, A. M., P. O'Regan, A. Fanning, C. O'Mahony, J. Mac sharry, A. Lyons, J. Bienenstock, L. O'Mahony and F. Shanahan. 2006. Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius. Immunol. 118(2):202-215. https://doi.org/10.1111/j.1365-2567.2006.02358.x
  24. Otten, W., B. Puppe, E. Kanitz, P. C. Schon and B. Stabenow. 2002. Physiological and behavioral effects of different success during social confrontation in pigs with prior dominance experience. Physiol. Behav. 1-15; 75(1-2):127-133. https://doi.org/10.1016/S0031-9384(01)00630-8
  25. Quinn, P. J., M. E. Carter, B. K. Markey and G. R. Carter. 1994. Pasteurella species In: Clinical Veterinary Microbiology, Mosby Yearbook, Wolfe Publishing, London. 254-258.
  26. Rinkinen, M., K. Jalava, E. Westermarck, S. Salminen and A. C. Ouwehand. 2003. Interaction between probiotic lactic acid bacteria and canine enteric pathogens: a risk factor for intestinal Enterococcus faecium colonization? Vet. Microbiol. 20; 92(1-2):111-119. https://doi.org/10.1016/S0378-1135(02)00356-5
  27. Timmerman, H. M., L. Mulder, H. Everts, D. C. van Espen, E. van der Wal, G. Klaassen, S. M. Rouwers, R. Hartemink, F. M. Rombouts and A. C. Beynen. 2005. Health and growth of veal calves fed milk replacers with or without probiotics. J. Dairy Sci. 88(6):2154-2165. https://doi.org/10.3168/jds.S0022-0302(05)72891-5
  28. Trocino, A., G. Xiccato, L. Carraro and G. Jimenez. 2005. Effect of diet supplementation with Toyocerin (Bacillus cereus var toyoi) on performance and health of growing rabbits. World Rabbit Sci. 13: 15-26.
  29. Yamano, T., H. Iino, M. Takada, S. Blum, F. Rochat and Y. Fnkushima. 2006. Improvement of the human intestinal flora by ingestion of the probiotic strain Lactobacillus johnsonii Lal. Br. J. Nutrit. 95(2):303-12. https://doi.org/10.1079/BJN20051507

Cited by

  1. Effect of diet supplementation with live yeast (Saccharomyces cerevisiae) on performance of rabbit does and their progenies vol.24, pp.1, 2016, https://doi.org/10.4995/wrs.2016.3917
  2. Effect of probiotic supplementation and genotype on growth performance, carcass traits, hematological parameters and immunity of growing rabbits under hot environmental conditions vol.88, pp.10, 2017, https://doi.org/10.1111/asj.12811
  3. Combined administration of bacteriocin- -producing, probiotic strain Enterococcus faecium CCM7420 with Eleutherococcus senticosus and their effect in rabbits vol.16, pp.4, 2013, https://doi.org/10.2478/pjvs-2013-0089
  4. Special effects of a complex probiotic containing cellulolytic bacteria Cellulomonas on actively growing rabbits vol.40, pp.3, 2013, https://doi.org/10.1134/s1062359013020167
  5. Effect of probiotic supplementation on growth performance, nutrient utilization and carcass characteristics of growing Chinchilla rabbits vol.45, pp.1, 2008, https://doi.org/10.1080/09712119.2016.1174126
  6. Can Enterocin M in Combination with Sage Extract Have Beneficial Effect on Microbiota, Blood Biochemistry, Phagocytic Activity and Jejunal Morphometry in Broiler Rabbits? vol.10, pp.1, 2008, https://doi.org/10.3390/ani10010115
  7. Autochtonous Strain Enterococcus faecium EF2019(CCM7420), Its Bacteriocin and Their Beneficial Effects in Broiler Rabbits—A Review vol.10, pp.7, 2008, https://doi.org/10.3390/ani10071188
  8. Effect of beneficial strain Enterococcus faecium EF9a isolated from Pannon White rabbit on growth performance and meat quality of rabbits vol.19, pp.1, 2008, https://doi.org/10.1080/1828051x.2020.1781553
  9. Beneficial effects of Enterococcus faecium EF9a administration in rabbit diet vol.28, pp.4, 2008, https://doi.org/10.4995/wrs.2020.11189
  10. Aspergillus awamori positively impacts the growth performance, nutrient digestibility, antioxidative activity and immune responses of growing rabbits vol.7, pp.1, 2008, https://doi.org/10.1002/vms3.345