Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
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Etiology and Pathogenesis of Recurrent Aphthous Stomatitis

재발성 아프타성 궤양의 원인과 기전

  • Suh, Bong-Jik (Department of Oral medicine, School of Dentistry, Chonbuk National University) ;
  • Lee, Kyung-Eun (Department of Oral medicine, School of Dentistry, Chonbuk National University)
  • 서봉직 (전북대학교 치의학전문대학원 구강내과학교실) ;
  • 이경은 (전북대학교 치의학전문대학원 구강내과학교실)
  • Published : 2008.06.30
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Abstract

Recurrent aphthous stomatitis is common oral disease in the world. It is characterized by multiple, recurrent, painful ulcer with circumscribed margins, erythematous haloes and yellow or grey floors. Patients with recurrent aphthous stomatitis suffer from its painful ulcer. But unfortunately, its etiology and pathogenesis is not clear and still unknown. So we review etiology and pathogenesis of recurrent aphthous ulcer and wish to propose direction of the future study.

재발성 아프타성 궤양은 흔히 발생하는 비특이적 구강점막질환이다. 궤양은 비각화 점막에 발생하고 일정시간이 흐른 후 치유가 되지만, 심한 통증으로 저작과 대화 등의 일상활동에 큰 지장을 초래한다. 그러나 아직까지 정확한 원인과 기전이 밝혀지지 않아 특별한 치료방법이 없어서 대증적인 방법으로 치료가 이루어진다. 이에 저자는 아프타성 궤양의 원인과 기전에 대한 문헌을 고찰하여 최신개념을 파악하고, 향후 나아가야 할 연구방향을 생각해 보고자 한다.

Keywords

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