Physical Therapy Korea (한국전문물리치료학회지)

Korean Research Society of Physical Therapy (한국전문물리치료학회)
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The Effects of Swimming and Low Power Laser on the Concentration of Interleukin-6 for Rheumatoid Arthritic Rats

수영과 저출력 레이저 치료가 류마티스 관절염 흰쥐의 혈청 인터루킨-6 농도에 미치는 영향

  • Park, Mi-Hee (Dept. of Physical Therapy, Masan College) ;
  • Rho, Min-Hee (Dept. of Physical Therapy, Catholic University of Pusan) ;
  • Lee, Hyun-Ok (Dept. of Physical Therapy, Catholic University of Pusan) ;
  • Koo, Bong-Oh (Dept. of Physical Therapy, Catholic University of Pusan) ;
  • Hwang, Soo-Myung (Dept. of Clinical Laboratory Science, Catholic University of Pusan)
  • 박미희 (마산대학 물리치료과) ;
  • 노민희 (부산가톨릭대학교 물리치료학과) ;
  • 이현옥 (부산가톨릭대학교 물리치료학과) ;
  • 구봉오 (부산가톨릭대학교 물리치료학과) ;
  • 황수명 (부산가톨릭대학교 임상병리학과)
  • Received : 2007.05.30
  • Accepted : 2007.12.03
  • Published : 2008.02.19
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Abstract

This study was designed to determine the effects of swimming and low power laser on rheumatoid arthritis in Sprague-Dawley rats. Rheumatoid arthritis was induced in 36 rats among 48 Sprague-Dawley rats by the subcutaneous injection of .05 $m{\ell}$ Freund's Complete Adjuvant into the right hind paw and .05 $m{\ell}$ Freund's Complete Adjuvant into the right hind knee joint capsule. A second injection was performed by the same method using .1 $m{\ell}$ Freund's Complete Adjuvant per a rat. Arthritic rats were divided into 8 groups: each 1 week and 2 weeks of arthritic swimming, arthritic laser, arthritic case control and normal group. In this study, several experimental tests were performed to determine the concentration of Interleukin-6, the space of the knee joint and the thickness of the hind paw. The concentration of Interleukin-6 and hind paw thickness decreased in the swimming group and laser group as compared to the control group. The space of the knee joint increased significantly after the swimming exercise. Swimming and low power laser therapy positively affect rheumatoid arthritis in rats affect by decreasing the concentration of Interleukin-6 and hind paw thickness, and increasing the space of the knee joint.

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