A BIOLOGIC STUDY ON TOOTHASH - PLASTER OF PARIS MIXTURE WITH ABSORBABLE COLLAGEN MEMBRANE IN THE TREATMENT OF PERI-IMPLANT DEFECTS

임플란트 주위염 치료시 치아회분말과 치과용 연석고의 혼합 매식의 골재생 효과

  • Choi, Hee-Yeon (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Hak-Kyun (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Su-Gwan (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Moon, Seong-Yong (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Sang-Yeol (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Park, Kwang-Bum (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Young-Min (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Lim, Seong-Chul (Department of Pathology, School of Medicine, Chosun University) ;
  • Kim, Eun-Seok (Department of Oral & Maxillofacial Surgery, College of Medicine, Chungnam National University) ;
  • Lee, Jeong-Hoon (Department of Oral & Maxillofacial Surgery, College of Medicine, Ilsan Paik Hospital, Inje University)
  • 최희연 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김학균 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김수관 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 문성용 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김상렬 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 박광범 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김용민 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 임성철 (조선대학교 의과대학 병리학교실) ;
  • 김은석 (충남대하교 의과대학 구강악안면외과학교실) ;
  • 이정훈 (인제대학교 의과대학 일산백병원 구강악안면외과학교실)
  • Published : 2008.03.31

Abstract

The purpose of this study was to evaluate histomorphometrically a toothash - plaster of Paris mixture associated with collagen membrane ($Bio-Gide^{(R)}$), regarding new bone formation in the peri-implantitis defects in dogs. Three mandibular molars were removed from 1-year-old mongrel dogs. After 2 months of healing, 2 titanium implants with sandblasted with large grit and acid etched (SLA) surface were installed in each side of the mandible. Experimental peri-implantitis was induced with ligatures after successful osseointegration. Ligatures were removed after identification of bone defect beneath the level of 5th thread of fixture on radiographic image. The mucoperiosteal flaps were elevated and the contaminated fixtures were treated with chlorhexidine and saline. The bone defects were assigned to one of the following treatments: no guided bone regeneration (GBR) procedure (group 1), GBR with Bio-$Oss^{(R)}$ and Bio-$Gide^{(R)}$ (group 2), or GBR with toothash - plaster of Paris mixture (TPM) and Bio-$Gide^{(R)}$ (group 3). The dogs were sacrificed after 8 or 16 months. The mean percentages of new bone formation within the limits of the 5 most coronal threads were $17.83{\pm}10.69$ (8 weeks) and $20.13{\pm}13.65$ (16 weeks) in group 1, $34.25{\pm}13.32$ (8 weeks) and $36.33{\pm}14.21$ (16 weeks) in group 2, and $46.33{\pm}18.39$ (8 weeks) and $48.00{\pm}17.78$ (16 weeks) in group 3, respectively. The present study confirmed statistically considerable new bone formation within the threads in group 3 compared with group 1 at 8 and 16 weeks (P<0.05). Although, data analysis did not reveal significant differences between group 2 and 3, the latter showed better results during the period of 8 or 16 weeks. Our findings support the effectiveness of TPM as a GBR material in the treatment of peri-implantitis bone defect.

Keywords

References

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