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Eye Irritation Test of Soyeom Pharmacopuncture Solution for Eye Drop

점안용 소염약침액의 안점막자극실험

  • Seo, Hyeong-Sik (Dept. of Ophthalmology, Otorhinolaryngology & Dermatology, College of Korean Medicine, Sangji University)
  • 서형식 (상지대학교 한의과대학 안이비인후피부과 교실)
  • Published : 2008.06.30

Abstract

Objectives This study was done to investigate the safety of Soyeom pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration(2005. 10. 21, KFDA 2005-60). After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't physical problem at 9 rabbits. 2. After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Soyeom pharmacopuncture solution didn't induced eye irritation in rabbits.

Keywords

References

  1. 약제학분과회. 제제학. 한림원. 2000:127,432
  2. 최규동 채병윤. 黃連, 진피, 秦皮散이 녹농균성 각막염에 미치는 효과에 관한 실험적 연구. 대한외관과학회지. 1999;12(1):18-35
  3. 이상준, 이주화. Soft Contact Lens 사용 중 발생된 녹농균성 각막염 3예. 대한안과학회지. 1990;31(5):681-6
  4. 식품의약품안전청 제2005-60호 의약품 등의 독성시험기준(2005. 10. 21. 개정)
  5. 서형식, 이용구, 노석선. 안병의 외치법에 대한 문헌고찰. 한방안이비인후피부과학회지. 1997;10(1):185-208
  6. 서형식. 소염약침액이 Staphylococcus aureus와 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구. 대한약침학회지. 2006;9(2):73-8 https://doi.org/10.3831/KPI.2006.9.2.073
  7. 서형식. 소염약침액, 황련해독탕, 황련이 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구. 대한약침학회지. 2006;9(2):87-92 https://doi.org/10.3831/KPI.2006.9.2.087
  8. 서형식. 소염약침액, 황련해독탕, 황련이 Staphylococcus epidermidis에 미치는 항균효과에 대한 실험적 연구. 한방안이비인후피부과학회지. 2006;19(2):19-25
  9. 윤미영, 유화승. 소염약침의 LPS로 유도된 RAW 264.7 세포의 염증성 사이토카인 발현에 미치는 영향. 대한약침학회지. 2007;10(3):21-8 https://doi.org/10.3831/KPI.2007.10.3.021

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  1. Testing of the Safety and the Effectiveness of Using Samjeong Pharmacopuncture Solution as Eye drops vol.15, pp.1, 2012, https://doi.org/10.3831/KPI.2012.15.1.023