Macromolecular Research

The Polymer Society of Korea (한국고분자학회)
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Synthesis and Microphase Separation of Biodegradable Poly($\varepsilon$-caprolactone)-Poly(ethylene glycol)-Poly($\varepsilon$-caprolactone) Multiblock Copolymer Films

  • You, Jae-Ho (Nanosphere Process and Technology Laboratory, Department of Chemical Engineering, Yonsei University) ;
  • Choi, Sung-Wook (Nanosphere Process and Technology Laboratory, Department of Chemical Engineering, Yonsei University) ;
  • Kim, Jung-Hyun (Nanosphere Process and Technology Laboratory, Department of Chemical Engineering, Yonsei University) ;
  • Kwak, Young-Tae (Department of Thoracic and Cardiovascular Surgery, East-West Neo Medical Center, College of Medicine, Kyung Hee University)
  • Published : 2008.10.31
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Abstract

Poly($\varepsilon$-caprolactone)-poly(ethylene glycol)-poly($\varepsilon$-caprolactone) (PCL-PEG-PCL) multiblock copolymers at various hydrophobic-hydrophilic ratios were successfully synthesized by the chain extension of triblock copolymers through isocyanate (hexamethylene diisocyanate). Biodegradable films were prepared from the resulting multiblock copolymers using the casting method. The mechanical properties of the films were improved by chain extension of the triblock copolymers, whereas the films prepared by the triblock copolymers were weak and brittle. Atomic force microscopy (AFM) of the multiblock copolymer film showed that the hydrophilic PEG had segregated on the film surface. This is consistent with the observed contact angle of the films.

Keywords

References

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