Nuclear Medicine and Molecular Imaging

The Korean Society of Nuclear Medicine (대한핵의학회)
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Current Status of Imaging Physics & Instrumentation In Nuclear Medicine

핵의학 영상 물리 및 기기의 최신 동향

  • Kim, Hee-Joung (Department of Radiological Science and Radiology, Yonsei University, Institute of Health Science, Yonsei University)
  • 김희중 (연세대학교 보건과학대학 방사선학과, 의과대학 영상의학과, 연세대학교 보건과학연구소)
  • Published : 2008.04.30
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Abstract

Diagnostic and functional imaging device have been developed independently. The recognition that combining of these two devices can provide better diagnostic outcomes by fusing anatomical and functional images. The representative examples of combining devices would be PET/CT and SPECT/CT. Development and their applications of animal imaging and instrumentation have been very active, as new drug development with advanced imaging device has been increased. The development of advanced imaging device resulted in researching and developing for detector technology and imaging systems. It also contributed to develop a new software, reconstruction algorithm, correction methods for physical factors, image quantitation, computer simulation, kinetic modeling, dosimetry, and correction for motion artifacts. Recently, development of MRI and PET by combining them together was reported. True integration of MRI and PET has been making the progress and their results were reported. The recent status of imaging and instrumentation in nuclear medicine is reported in this paper.

지난 몇 년 동안 핵의학 영상 물리 및 기기 관련 융합영상기기 분야에 많은 발전이 있었다. 최근 몇 년 동안 국내 PET/CT 설치의 급속한 증가는 이들의 임상에서의 역할 및 그 중요성을 입증하고 있다. 그러나 PET/CT는 고가이고, 임상적으로 아직도 그 유용성이 입증되는 과정에 있으며, 특히 치료계획을 위한 장비로는, 미국의 경우 다소 많이 설치되었다는 평가가 공존하고 있다. 또한 저가로 해 결할 수 있는 소프트웨어 융합도 가능하기 때문에 PET 대신 반드시 PET/CT가 필요하다는 주장에는 위의 관점에서 그 한계가 있을 수 있다. 그림에도 불구하고 PET/CT 설치는 계속 증가하고 있어 영상획득 또는 영상판독 모두 PET과 CT 분야의 훈련과 교육이 매우 중요하며 이에 대한 지침서가 발간되었다. PET/CT에 비하여 SPECT/CT는 발전속도가 다소 떨어지지만 이에 대한 지침서도 발간되었다. PET/CT와 SPECT/CT 모두 CT는 앞 부분에 PET과 SPECT는 뒷부분에 설치된다. 이는 환자 영상을 얻을 때 동시에 얻는 것이 아니고 CT영상을 얻은 후 PET과 SPECT영상을 얻게되는 단점이 있다. 이와는 달리 MRI/PET경우 뇌영상을 얻을 때 동시에 MRI와 PET영상을 얻을 수 있어 뇌영상 연구에 큰 도움이 될 것으로 예상하고 있다. 앞으로 기술이 발전함에 따라 전신용 MRI/PET과 유방영상을 위한 PET/US 융합영상장치의 개발 가능성이 매우 높다. 이와 함께 SPECT/CT, PET/CT 및 MRI/PET 기기의 발전도 계속될 것으로 판단된다. 핵의학 영상 물리 및 기기 분야는 최첨단 융합영상 장치의 개발과 함께 하드웨어, 소프트웨어 물리적 특성에 대한 보정기술, 영상 재구성 분야의 다양한 연구도 많은 진전이 필요하다. 또한 영상기기의 설계 및 정량화 기법을 연구하기 위한 몬테카를로 시뮬레이션, 영상장비의 성능평가, 동력학 분석, 선량평가, 움직임 보정 및 융합영상의 정량화 및 분석 기법에 대한 연구도 더욱 활발히 진행될 것으로 예측된다.

Keywords

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