Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Screening of Antioxidant Activity from Medicinal Plant Extracts

약용식물 추출물로부터 항산화활성 탐색

  • Kwon, Ji-Wung (Medicinal Resources Research Center, Wonkwang University, College of Life Science and Natural Resources, Wonkwang University) ;
  • Lee, Eoh-Jin (Medicinal Resources Research Center, Wonkwang University, College of Life Science and Natural Resources, Wonkwang University) ;
  • Kim, Youn-Chul (Medicinal Resources Research Center, Wonkwang University, College of Pharmacy, Wonkwang University) ;
  • Lee, Hye-Suk (Medicinal Resources Research Center, Wonkwang University, College of Pharmacy, Wonkwang University) ;
  • Kwon, Tae-Oh (Medicinal Resources Research Center, Wonkwang University, College of Life Science and Natural Resources, Wonkwang University)
  • 권지웅 (원광대학교 의약자원연구센터, 원광대학교 생명자원과학대학) ;
  • 이어진 (원광대학교 의약자원연구센터, 원광대학교 생명자원과학대학) ;
  • 김윤철 (원광대학교 의약자원연구센터, 원광대학교 약학대학) ;
  • 이혜숙 (원광대학교 의약자원연구센터, 원광대학교 약학대학) ;
  • 권태오 (원광대학교 의약자원연구센터, 원광대학교 생명자원과학대학)
  • Published : 2008.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was carried out to search the natural antioxidants from the 36 medicinal plants. $IC_{50}$ values of linoleic acid peroxidation inhibition to the BHA, BHT and ${\alpha}-tocopherol$ showed $7.2{\mu}g/ml$, $7.3{\mu}g/ml$, and $26.6{\mu}g/ml$, but hexane extract of Zingiber officinale showed $13.2{\mu}g/ml$, EtOAc extracts of Phellinus linteus, Morus alba, Zingiber officinale and butanol extract of Diospyros kaki showed $15.9{\mu}g/ml$, $16.9{\mu}g/ml$, $20.1{\mu}g/ml$, and $21.5{\mu}g/ml$ respectively. $IC_{50}$ values of DPPH radical scavenging activity of BHA, BHT and $\alpha$-tocopherol showed $14.9{\sim}27.7{\mu}g/ml$, but EtOAc extract of Paeonia suffruticosa showed the lowest $6.5{\mu}g/ml$ than those of other extracts, EtOAc extracts of Camellia sinensis, Salvia miltiorrhiz, and Phellinus linteus showed $8.0{\mu}g/ml$, $11.5{\mu}g/ml$, and $13.0{\mu}g/ml$ respectively.

Keywords

References

  1. Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., Mazur, M., Telser, J. (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 39: 44-84 https://doi.org/10.1016/j.biocel.2006.07.001
  2. Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., Mazur, M. (2006) Free radicals, metals and antioxidants in oxidativ stress-induced cancer. Chem. Biol. Interact. 160: 1-40 https://doi.org/10.1016/j.cbi.2005.12.009
  3. Branen, A. L. (1975) Toxicology and biochemistry of butylated hydroxy anisole and butylated hydroxytoluene. J. Am. Oil Chem. Soc. 52: 59-63 https://doi.org/10.1007/BF02901825
  4. Choe, S. Y. and Yang, K. H. (1982) Toxicological studies of antioxidants butylated hydroxytoluene(BHT) and butylated hydroxy anisole(BHA). Korean J. Food Sci. Technol. 14: 283-288
  5. Farag, R. S., Badei, A. Z. M. A., Hewedi, F. M., El-Baroty, G. S. A. (1989) Antioxidant activity of some spice essential oils on linoleic acid oxidation in aqueous media. J. Am. Oil. Chem. Soc. 66: 792-799 https://doi.org/10.1007/BF02653670
  6. Farag, R. S., Badei, A. Z. M. A., El-Baroty, G. S. A. (1989) Influence of thyme and clove essential oils on cottonseed oil oxidation. J. Am. Oil. Chem. Soc. 66: 800-804 https://doi.org/10.1007/BF02653671
  7. Lee, Y. S. (2007) Antioxidative and physiological activity of extracts of Angelica dahurica leaves. Korean J. Food Preserv. 14(1): 78-86
  8. Maeng, Y. S., Park. H. K. (1991) Antioxidant activity of ethanol extract from Dodok(Codonopsis lanceolata). Korean J. Food Sci. Technol. 23: 311-316
  9. Chi, H. Y., Kim, K. H., Kong, W. S., Kim, S. L., Kim, J. A., Chung, I. M., Kim, J.T. (2005) Antioxidant activity and total phenolic compounds of P. eryngii spp. extracts. Korean J. Crop Sci. 50(S): 216-219
  10. Lim, J. A., Yun, B. W., Baek, S. H. (2007) Antioxidant activity and nitrite scavenging ability of methanol extract from Salvia plebeia R. Br. Korean J. Medicinal Crop Sci. 15(3): 183-188
  11. Moon, G. S., Ryu, B. M., Lee, M. J. (2003) Components antioxidative activities of Buchu (Chinese chives) harvested at different times. Korean J. Food Sci. Technol. 35: 493-498
  12. Jung, G. T., Ju, I. O., Choi, J. S., Hong, J. S. (2000) The antioxidative, antimicrobial and nitrate scavenging effects of Schizandra Chinesis RUPRECHT (Omija) seed. Korean J. Food Sci. Technol. 32: 928-935
  13. Kim, S. E., Rhyu, D. Y., Takako, Y., Park, J. C. (2007) Antioxidant effect of Alisma plantago-aquatica var. orientale and its main component. Kor. J. Pharmacogn. 38(4): 372-375
  14. Park, J. H., Kang, K. C., Baek, S. B., Lee, Y. H., Rhee, K. S. (1991) Separation of antioxidant compounds from edible marine algae. Korean J. Food Sci. Technol. 23: 256-261
  15. Choi, J., Shin, D. H., Chang, Y. S., Shin, J. I. (1992) Screening of natural antioxidant from plant and their antioxdidantive effect. Korean J. Food Sci. Technol. 24: 142-148
  16. Inatani, R., Nakatani, N., Fuwa, H. (1983) Antioxidative effect of the constituents of rosemary (Rosmarinus offcinalis L.) and their derivatives. Agricultural and Biological Chemistry 47: 521-528 https://doi.org/10.1271/bbb1961.47.521
  17. Choi, J. S., Park, J. H., Kim, H. G., Young, H. S., Mun, S. I. (1993) Screening for antioxidant activitiy of plants and marine algae and its active principles from Prunus daviana. Korean journal of Pharmacology 24: 299-303
  18. Lee, E. S., Seong, N. S., Park, C. G., Seong, J. S. (2002) Screening for antioxidative activity of oriental medicinal plant materials. Korean J. Medicinal Crop Sci. 10(3): 171-176
  19. Han, S. H., Woo, N. R. Y., Lee, S. D., Kang, M. H. (2006) Antioxidaitive and antibacterial activities of endemic plants extracts in korea. Korean J. Medicinal Crop Sci. 14(1): 49-55
  20. Kim, E. Y., Baik, I. H., Kim, J. H., Kim, S. R., Rhyu, M. R. (2004) Screening of the antioxidant activity of some medicinal plants. Korean J. Food Sci. Technol. 36(2): 333-338