Effects of Complex Food Ingredient Composed of Garlic and Fermented Soybean Hypocotyl on the Serum Lipid Profiles of the Rats Fed High-Fat Diet

마늘과 대두배아 발효물로 구성된 복합 식품소재가 고지방 식이를 섭취한 흰쥐의 혈중 지질 성분에 미치는 영향

  • Choi, Hyung-Taek (Shin Won Food Industry Co., Ltd.) ;
  • Kim, Eui-Su (Shin Won Food Industry Co., Ltd.) ;
  • Ham, Seung-Shi (Department of Food Science & Biotechnology, Kangwon National University) ;
  • Park, Seung-Yong (College of Veterinary Medicine, Konkuk University) ;
  • Chung, Ha-Yull (Department of Food Science & Biotechnology and Food & Bioproduts Research Center, Hankyong National University)
  • 최형택 ((주)신원 에프아이) ;
  • 김의수 ((주)신원 에프아이) ;
  • 함승시 (강원대학교 식품생명공학과) ;
  • 박승용 (건국대학교 수의과대학) ;
  • 정하열 (한경대학교 식품생물공학과 및 식품생물산업연구소)
  • Published : 2008.04.30

Abstract

Garlic that has been reacted with fermented soybean hypocotyl, termed Bio-Garlic, contains 6 times more allithiamine than garlic alone, and it was prepared as a complex food ingredient. To examine the effects of Bio-Garlic on obesity and hyperlipidemia, rats were fed a high-fat diet for 8 weeks. Bio-Garlic arrested increases in body weight without affecting feed intake in the rats. The Bio-Garlic also lowered serum levels of total cholesterol and triglycerides, while increased serum HDL-cholesterol levels. The atherogenic index of the Bio-Garlic treated group decreased, suggesting that Bio-Garlic has the potential to be marketed as a functional health food ingredient with beneficial effects on the circulatory system.

마늘과 대두배아의 발효물을 반응시켜 allithiamine의 함량이 기존의 마늘에 비해 6배 증가한 바이오갈릭을 제조하였다. 바이오갈릭이 고지방 식이에 의해 유발되는 과체중 및 고지혈증에 미치는 영향을 조사하기 위하여 고지방에 1%의 바이오 갈릭이 포함된 식이를 제조하고 이를 흰쥐에 8주간 공급하였다. 바이오갈릭은 흰쥐의 식이 섭취량에는 영향을 끼치지 않았으나 체중의 증가 정도를 유의적으로 억제하였다. 또한 혈중 총콜레스테롤 및 중성지방의 수준을 저하시켰으며, HDL-콜레스테롤의 수준을 증가시키는 효과를 나타내었다. 이와 같이 바이오갈릭에는 동맥경화지수를 감소시키는 생리활성이 있는 것을 알 수 있었으며 향후 혈행개선 효과를 갖는 건강 지향적 식품소재로서의 사용에 대한 가능성이 있음을 확인할 수 있었다.

Keywords

References

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