The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Effects of Cardiotonic Pills (CP) on Serum Lipid Level in Hyperlipidemic Rats

심적환이 고지혈증 흰쥐의 혈중 지질 변화에 미치는 영향

  • Kim, Hyung-Woo (Research Center of Industrial Accelerators) ;
  • Kwon, Tae-Woo (College of Korean Medicine, Dong-Eui University) ;
  • Jung, Sun (College of Korean Medicine Dongshin University) ;
  • Cho, Su-In (School of Oriental Medicine, Pusan National University) ;
  • Kim, Young-Gyun (College of Korean Medicine, Dong-Eui University) ;
  • Bong, Seung-Jeon (College of Korean Medicine, Dong-Eui University)
  • 김형우 (산업용가속기이용 생물연구센터) ;
  • 권태우 (동의대학교 한의과대학) ;
  • 정선 (동신대학교 한의과대학) ;
  • 조수인 (부산대학교 학의학전문대학원) ;
  • 김영균 (동의대학교 한의과대학) ;
  • 봉승전 (동의대학교 한의과대학)
  • Published : 2008.06.30
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Abstract

Objectives : SimJeok-Hwan (CP, Cardiotonic Pills) is the traditional remedy to treat patients with coronary arteriosclerosis, angina pectoris and hyperlipidemia. This study was designed to investigate the effects of CP on changes in serum cholesterol levels in hyperlipidemic rats. Methods : In this study, we investigated the effects of CP on changes in body weights, food and water uptake, fasting blood glucose, total cholesterols, HDL-cholesterol, and triglyceride in hyperlipidemic rats. Results : In our results, body weights of hyperlipidemic rats induced by high fat diet did not changed, and treatment with CP did not affect body weights in hyperlipidemic rats. For experimental period, food and water uptake in CP administered group were the same as those in hyperlipidemic control group. In this experiment, treatment with CP decreased total cholesterol and triglyceride in serum which elevated by high fat diet respectively. Conclusions : These results suggest that CP is useful to treat patients with disease related to hyperlipidemia because CP can decrease cholesterol in serum

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