Food Science of Animal Resources (한국축산식품학회지)

Korean Society for Food Science of Animal Resources (한국축산식품학회)
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Effects of Goat Milk Yogurt Supplemented with Citrus Concentrate on Blood Glucose and Serum Lipids in Diabetic Rats

밀감농축액 첨가 산양발효유가 당뇨병 유발 랫드의 혈당 및 혈액지질에 미치는 영향

  • 함준상 (축산과학원 축산생명환경부) ;
  • 신지혜 (축산과학원 축산생명환경부) ;
  • 장애라 (축산과학원 축산생명환경부) ;
  • 정석근 (축산과학원 축산생명환경부) ;
  • 박광욱 ((주)엠젠 생명과학연구소) ;
  • 김현욱 ((주)엠젠 생명과학연구소) ;
  • 강수연 (충북대학교 수의과대학) ;
  • 황혜중 (충북대학교 수의과대학) ;
  • 이완규 (충북대학교 수의과대학)
  • Published : 2008.10.31
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Abstract

The effects of fermented goat milk supplemented with citrus concentrate on blood glucose levels in streptozotocin-nicotinamide-induced diabetic rats were examined. Streptozotocin-nicotinamide-induced diabetic rats (type II) were divided into five experimental groups treated with metformin, goat milk, fermented goat milk, fermented goat milk containing citrus concentrate, or no supplementation (control). The rats in each group were examined weekly for blood levels of glucose, total cholesterol, triglyceride. HDL-cholesterol, LDL-cholesterol. and body weight. On the $24^{th}$ day of the experiment, an oral glucose tolerance test (OGTT) was carried out. Administration of fermented goat milk to the diabetic rats significantly decreased blood glucose and triglyceride levels, while administration of metformin (33.3 mg/kg body weight) did not significantly lower blood glucose levels. Fermented goat milk containing citrus concentrate caused a significant decrease in blood glucose levels in the OGTT at 30 min. This study shows that supplementation with fermented goat milk containing citrus concentrate may be a practical method of reducing blood glucose levels in type II diabetics.

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References

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