Relationship between Low Back Pain and Lumbar Paraspinal Muscles Fat Change in MRI

편측 요통을 호소하는 환자에 있어서 척추 주위 근육의 지방량과 통증과의 관계

  • Kim, Ha-Neul (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Kim, Kyoung-Hun (Dept. Physical Education, Graduate School of Yon-Sei University) ;
  • Kim, Joo-Won (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Jin, Eun-Seok (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Ha, In-Hyuk (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Koh, Dong-Hyun (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Hong, Soon-Sung (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital) ;
  • Kwon, Hyeok-Joon (Dept. of Oriental Rehabilitation Medicine, Ja-Seng Oriental Hospital)
  • 김하늘 (자생한방병원 한방재활의학과) ;
  • 김경훈 (연세대학교 체육 교육 대학원) ;
  • 김주원 (자생한방병원 한방재활의학과) ;
  • 진은석 (자생한방병원 한방재활의학과) ;
  • 하인혁 (자생한방병원 한방재활의학과) ;
  • 고동현 (자생한방병원 한방재활의학과) ;
  • 홍순성 (자생한방병원 한방재활의학과) ;
  • 권혁준 (자생한방병원 한방재활의학과)
  • Received : 2008.10.24
  • Accepted : 2009.01.18
  • Published : 2009.01.13

Abstract

Objectives : Low back pain(LBP) is a common disabling disease in clinical practice and loss of working hours due to this condition is huge. The aim of this study was to determine if there was an association between fat deposit of paraspinal muscles as observed on MRI scans in patients presenting with unilateral LBP. Methods : 24 patients who visiting our hospital with a clinical presentation of unilateral LBP were recruited to the study. Patients were between 20 and 30 years and had a history of unilateral LBP within 12 months. After MRI scaning, the images were saved in DICOM file format for Picture Archiving and Communication System(PACS). The percentage of fat infiltrated area was measured using a pseudocoloring technique. Data were analyzed comparing the fat deposits of the muscles on the symptomatic and asymptomatic sides. Paired t-test was used to find the difference between the measurements of fat tissue in individual patients. Results : The amount of fat in the symptomatic side was $7.6{\pm}4.51%$, asymptomatic side was $6.7{\pm}4.29%$. There were increases, statistically significant, in the fat changes of the paraspinal muscles at the L4-5 disc level(P <0.05). Also, men were likely than women to have more fat deposit in symptomatic side(men $8.5{\pm}5.1%$, women $6.5{\pm}3.6%$). Conclusions : The amount of fat in the symptomatic side shows significantly increased than asymptomatic side in the paraspinal muscles at the L4-5 disc level. It suggested that fat infiltration in the muscles associated with LBP. Further studies will be needed to confirm the relationship between the muscle fatty changes and LBP in the large sample size. In addition, the correlation of pain severity with fat infiltration needs to be addressed.

목적 : 요통은 임상에서 가장 흔하게 접할 수 있는 질환이며, 동시에 통증으로 인한 근무 결손도나 생활 불편감이 높은 질병이다. 그래서, 많은 연구들이 요통을 일으키는 원인 혹은 악화시키는 유발 인자를 밝혀내려는데 초점이 맞추어져 있다. 이번 연구의 목적은 편측 요통을 호소하는 환자에 있어서 MRI에서 조사된 척추 주위 근육의 지방량과 통증과의 관계에 대해서 알아보는데 있다. 방법 : 2007년 11월부터 2008년 4월까지 본원에 요통으로 내원한 환자를 대상으로, 편측 요통을 호소하며, 체질량 지수가 $25kg/m^2$ 이하이며, 만 20세이상 40세미만인 환자 24명을 대상으로 연구를 진행하였다. MRI에서 조사되어진 L4-5 디스크 레벨의 척추 주위 근육의 지방량을 객관적인 pseudocoloring technique을 이용해 측정하고, paired t-test로 결과를 분석하여 요통이 유발된 측과 지방량의 관계에 대해서 연구하였다. 결과 : 요통이 있는 측의 지방량과 요통이 없는 측의 지방량을 측정하여 데이터를 분석하였다. 양측의 지방량과 통증의 유무에 대한 관계는 통계적으로 유의한 수치를 나타냈다(P <0.05). 요통이 있는 측과 없는 측과의 성별, 나이, BMI의 통계적인 차이는 없었으며, 지방량 측정시 남자들이 여자들에 비해 지방량이 더 높게 측정되었다(남자 $8.5{\pm}5.1%$, 여자 $6.5{\pm}3.6%$). 결론 : 이 연구를 통해 척추 주위 근육의 지방량과 요통에 대한 상관성의 증거를 제시하였다. 잘 선별되어진 환자의 MRI를 통해 객관적인 방법으로 지방량을 체크를 하였으며, 추후 더 많은 개체수를 이용해 보다 더 정확한 관련성을 파악하고, 나아가 지방량에 따른 통증 강도의 상관성에 대해서 연구가 필요하리라 생각된다.

Keywords

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