Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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Comparison of Treatment Effect of the Dried Bovine Amniotic Membrane and the Cultured Allogenic Keratinocytes in the Partial Thickness Burn Management

부분층 화상에 적용한 건조소양막과 동종배양표피세포의 치료효과 비교

  • Yeo, Hyeon Jung (Deparment of Plasic and Reconstructive Surgery Keimyung University School of Medicine) ;
  • Kim, Jun Hyung (Deparment of Plasic and Reconstructive Surgery Keimyung University School of Medicine) ;
  • Jung, Yung Jin (Deparment of Plasic and Reconstructive Surgery Keimyung University School of Medicine) ;
  • Son, Dae Gu (Deparment of Plasic and Reconstructive Surgery Keimyung University School of Medicine) ;
  • Han, Ki Hwan (Deparment of Plasic and Reconstructive Surgery Keimyung University School of Medicine)
  • 여현정 (계명대학교 의과대학 성형외과학교실) ;
  • 김준형 (계명대학교 의과대학 성형외과학교실) ;
  • 정영진 (계명대학교 의과대학 성형외과학교실) ;
  • 손대구 (계명대학교 의과대학 성형외과학교실) ;
  • 한기환 (계명대학교 의과대학 성형외과학교실)
  • Published : 2009.07.15
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Abstract

Purpose: In the partial thickness burn management, despite of several advantages, the use of human amniotic membrane has been limited. The authors applied dried bovine amniotic membrane(DBAM) to overcome disadvantages of amniotic membrane for partial thickness burn and compared the effectiveness with cultured allogenic keratinocytes(CAK) that have been recently used for the management of burn. Methods: 16 patients with partial thickness burn, the mean age of 38 ranging 12 to 59 years, between August 2007 and May 2008 were assigned to this study. Either DBAM or CAK was applied, and the secondary dressing was removed on the following day. To compare treatment effect, time for epithelization, Vancouver scar scale and chromameteric results were evaluated. Results: The time for epithelization of DBAM was 10.1 days, that of CAK was 9.1 days, and they were shorter than the previous 2 - 3 weeks. At the follow up Vancouver scar scale was 2.8 for DBAM and 3.0 points for CAK and showed good results. The result of chromameter showed that the $L^*$, $a^*$, and $b^*$ values of the area applied DBAM were 60.1, 13.6, and 13.3, respectively, and the values of the area applied CAK were 60.1, 12.4, and 12.4, respectively. It was found that the skin color of the healed area after burn was darker, the redness was higher, and the yellowness was lower. After dressing, significant side effects were not observed, and in the cases of applying CAK, it was inconvenient as the moving area had to be fixed. Conclusion: With CAK, DBAM has several advantages such as the shortening of the epithelization period, reduction of scar and pigmentation, and convenient application, etc. Thus it is an effective method for the partial thickness burn management.

Keywords

References

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