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Central Functions of Amino Acids for the Stress Response in Chicks

  • Yamane, H. (Laboratory of Advanced Animal and Marine Bioresources, Faculty of Agriculture, Kyushu University) ;
  • Kurauchi, I. (Laboratory of Advanced Animal and Marine Bioresources, Faculty of Agriculture, Kyushu University) ;
  • Denbow, D.M. (Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University) ;
  • Furuse, Mitsuhiro (Laboratory of Advanced Animal and Marine Bioresources, Faculty of Agriculture, Kyushu University)
  • 발행 : 2009.02.01

초록

The nutritional significance of essential amino acids, as well as non-essential amino acids, is well documented in poultry production with regards to growth performance and protein accretion. However, the function of amino acids in the stress response is still unclear. L-Pipecolic acid, a L-lysine metabolite in the brain, induced a hypnotic and sedative effect acting via the ${\gamma}$- aminobutyric acid receptors. L-Arginine also induced a sedative effect via its metabolism to L-ornithine. In addition, three-carbon nonessential amino acids like L-alanine, L-serine and L-cysteine also induced sedative effects. These facts suggest that the requirement for amino acids in both essential and non-essential types may require reconsideration to add the concept of stress amelioration in the future.

키워드

참고문헌

  1. Asechi, M., I. Kurauchi, S. Tomonaga, H. Yamane, R. Suenaga, Y. Tsuneyoshi, D. M. Denbow and M. Furuse. 2008, Relationships between the sedative and hypnotic effects of intracerebroventricular administration of L-serine and its metabolites, pyruvate and the derivative amino acids contents in the neonatal chicks under acute stressful conditions, Amino Acids 34:55-60 https://doi.org/10.1007/s00726-007-0596-y
  2. Asechi, M., S. Tomonaga, T. Tachibana, L. Han, K. Hayamizu, D. M. Denbow and M. Furuse. 2006,Intracerebroventricular injection of L-serine analogs and derivatives induces sedative and hypnotic effects under an acute stressful condition in neonatal chicks,Behav. Brain Res. 1701:71-77
  3. Chang, Y. F. 1978, Lysine metabolism in the rat brain: Bloodbrain- barrier transport, Formation of pipecolic acid and human hyperpipecolatemia, J. Neurochem. 30:355-360 https://doi.org/10.1111/j.1471-4159.1978.tb06537.x
  4. Chang, Y. F. 1982, Lysine metabolism in the human and the monkey: demonstration of pipecolic acid formation in the brain and other organs, Neurochem. Res. 7:577-588 https://doi.org/10.1007/BF00965124
  5. Chromiak, J. A. and J. Antonio. 2002, Use of amino acids as growth hormone-releasing agents by athletes, Nutrition 18: 657-661 https://doi.org/10.1016/S0899-9007(02)00807-9
  6. Contreras, P. C. 1990, D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia, Neuropharmacology 29:291-293 https://doi.org/10.1016/0028-3908(90)90015-J
  7. Cook, S. P., I. Galve-Roperh, A. Martinez del Pozo and I. Rodriguez-Crespo. 2002, Direct calcium binding results in activation of brain serine racemase, J. Biol. Chem. 277:27782-27792 https://doi.org/10.1074/jbc.M111814200
  8. de Koning, T. J., M. Duran, L. van Maldergem, M. Pineda, L. Dorland, R. Gooskens, J. Jaeken and B. T. Poll-The. 2002, Congenital microcephaly and seizures due to 3- phosphoglycerate dehydrogenase deficiency: outcome of treatment with amino acids, J. Inherit Metab. Dis. 25:119-125 https://doi.org/10.1023/A:1015624726822
  9. de Koning, T. J., L. W. Klomp, A. C. van Oppen, F. A. Beemer, L. Dorland, I. E. T. van den Berg and R. Berger. 2004, Prenatal and early postnatal treatment in 3-phosphoglyceratedehydrogenase deficiency, Lancet 364: 2221-2222 https://doi.org/10.1016/S0140-6736(04)17596-X
  10. Feltenstein, M. W., L. C. Lambdin, M. Ganzera, H. Ranjith, W. Dharmaratne, N. P. Nanayakkara, I. A. Khan and K. J. Sufka. 2003, Anxiolytic properties of Piper methysticum extract samples and fractions in the chick social-separation-stress procedure, Phytother. Res. 17:210-216 https://doi.org/10.1002/ptr.1107
  11. Furuse, M., T. Takagi, T. Bungo and D. M. Denbow. 2006. Functions of L-pipecolic acid as an L-lysine metabolite in the brain. In: Trends in brain mapping research (Ed. F. J. Chen), pp.145-165. NOVA Science Publishers Inc., Hauppauge NY, USA
  12. Giacobini, E., Y. Nomura and T. Schmidt-Glenewinkel. 1980, Pipecolic acid: Origin, biosynthesis and metabolism in the brain, Cell. Molec. Biol. 26:135-146
  13. Gonzalez, S. V., H. T. N. Nguyen, F. Rise and B. Hassel. 2005, Brain metabolism of exogenous pyruvate, J. Neurochem. 95:284-293 https://doi.org/10.1111/j.1471-4159.2005.03365.x
  14. Hamasu, K., T. Haraguchi, Y. Kabuki, N. Adachi, S. Tomonaga, H. Sato, D. M. Denbow and M. Furuse. 2009. L-Proline is a sedative regulator of acute stress in the brain of neonatal chicks. Amino Acids, in press
  15. Han, Y. and D. H. Baker. 1993, Effects of excess methionine or lysine for broilers fed a corn-soybean meal diet, Poult. Sci. 72:1070-1074 https://doi.org/10.3382/ps.0721070
  16. Hashimoto, A. 2002, Effect of the intracerebroventricular and systemic administration of L-serine on the concentrations of D- and L-serine in several brain areas and periphery of rat, Brain Res. 955:214-220 https://doi.org/10.1016/S0006-8993(02)03466-2
  17. Hashimoto, A., M. Yoshikawa, A. Niwa and R. Konno. 2005, Mice lacking D-amino acid oxidase activity display marked attenuation of stereotypy and ataxia induced by MK-801, Brain Res. 1033:210-215 https://doi.org/10.1016/j.brainres.2004.11.031
  18. Hassel, B. 2001, Pyruvate carboxylation in neurons, J. Neurosci. Res. 66:755-762 https://doi.org/10.1002/jnr.10044
  19. Hutzler, J. and J. Dancis. 1968, Conversion of lysine to saccharopine by human tissues, Biochim. Biophys. Acta 158: 62-69 https://doi.org/10.1016/0304-4165(68)90072-X
  20. Jaeken, J., M. Detheux, L. van Maldergem, M. Foulon, H. Carchon and E. van Schaftingen. 1996, 3-Phosphoglycerate dehydrogenase deficiency: an inborn error of serine biosynthesis, Arch. Dis. Child. 74:542-545 https://doi.org/10.1136/adc.74.6.542
  21. Kemp, J. A. and P. D. Leeson. 1993, The glycine site of the NMDA receptor-five years on, Trends Pharmacol. Sci. 14:20-25
  22. Koga, Y., H. Takahashi, D. Oikawa, T. Tachibana, D. M. Denbow and M. Furuse. 2005, Brain creatine functions to attenuate acute stress responses through GABAnergic system in chicks, Neuroscience 132:65-71 https://doi.org/10.1016/j.neuroscience.2005.01.004
  23. Konno, R. 2003, Rat cerebral serine racemase: amino acid deletion and truncation at carboxy terminus, Neurosci. Lett. 349:111-114 https://doi.org/10.1016/S0304-3940(03)00801-2
  24. Koutoku, T., H. Takahashi, S. Tomonaga, D. Oikawa, S. Saito, T. Tachibana, L. Han, K. Hayamizu, D. M. Denbow and M. Furuse. 2005, Central administration of phosphatidylserine attenuates isolation stress induced behavior in chicks, Neurochem. Int. 47:183-189 https://doi.org/10.1016/j.neuint.2005.03.006
  25. Kurauchi, I., M. Asechi, T. Tachibana, L. Han, K. Hayamizu, D. M. Denbow and M. Furuse. 2006, Intracerebroventricular injection of L-alanine induces a sedative effect under an acute stressful condition in neonatal chicks. J. Poult. Sci. 43:384-387 https://doi.org/10.2141/jpsa.43.384
  26. Kurauchi, I., M. Asechi, T. Tachibana, L. Han, K. Hayamizu, D. M. Denbow and M. Furuse. 2007, Intracerebroventricular injection of tryptophan, but not lysine or methionine, induces a sedative effect during an acute stressful condition in neonatal chicks, J. Appl. Anim. Res. 31:25-28 https://doi.org/10.1080/09712119.2007.9706623
  27. McBain, C. J. and M. L. Mayer. 1994, N-methyl-D-aspartic acid receptor structure and function, Physiol. Rev. 74:723-760 https://doi.org/10.2466/pr0.1994.74.3.723
  28. Morris, S. M. Jr. 2004, Enzymes of arginine metabolism, J. Nutr.134:2743S-2747S
  29. Neu, A., H. Neuhoff, G. Trube, S. Fehr, K. Ullrich, J. Roeper and D. Isbrandt. 2002, Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism, Neurobiol. Dis. 11:298-307 https://doi.org/10.1006/nbdi.2002.0547
  30. Nomura, Y., T. Schmidt-Glenewinkel and E. Giacobini. 1978, In vitro formation of piperidine, cadaverine and pipecolic acid in chick and mouse brain during development, Dev. Neurosci. 1:239-249 https://doi.org/10.1159/000112578
  31. Olsen, R. W. and T. M. DeLorey. 1999, GABA and glycine. In: Basic neurochemistry. Molecular, cellular and medical aspects (Ed. G. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher and M. D. Uhler). Sixth Edition. pp. 335-346, Lippincott-Raven Publishers. New York
  32. Shigemi, K., Y. Tsuneyoshi, K. Hamasu, L. Han, K. Hayamizu, D. M. Denbow, M. Furuse. 2008, L-Serine induces sedative and hypnotic effects acting at GABA(A) receptors in neonatal chicks, Eur. J. Pharmacol. 599:86-90 https://doi.org/10.1016/j.ejphar.2008.09.036
  33. Stifel, F. B. and R. H. Herman. 1971, Histidine metabolism, Am. J. Clin. Nutr. 24:207-217
  34. Suenaga, R., S. Tomonaga, H. Yamane, I. Kurauchi, Y. Tsuneyoshi, H. Sato, D. M. Denbow and M. Furuse. 2008a, Intracerebroventricular injection of L-arginine induces sedative and hypnotic effects under an acute stress in neonatal chicks, Amino Acids 35:139-146 https://doi.org/10.1007/s00726-007-0610-4
  35. Suenaga, R., H. Yamane, S. Tomonaga, M. Asechi, N. Adachi, Y. Tsuneyoshi, I. Kurauchi, H. Sato, D. M. Denbow and M. Furuse. 2008b, Central L-arginine reduced stress responses are mediated by L-ornithine in neonatal chicks, Amino Acids35:107-113 https://doi.org/10.1007/s00726-007-0617-x
  36. Takagi, T., R. Ando, A. Ohgushi, T. Yamashita, E. Dobashi, H. Hussain-Yusuf, R. Onodera, T. Bungo, H. Sato and M. Furuse. 2001, Intracerebroventricular injection of pipecolic acid inhibits food intake and induces sleeping-like behaviors in the neonatal chick, Neurosci. Lett. 310:97-100 https://doi.org/10.1016/S0304-3940(01)02059-6
  37. Takagi, T., T. Bungo, T. Tachibana, E.-S. Saito, S. Saito, I. Yamasaki, S. Tomonaga, D. M. Denbow and M. Furuse. 2003, Intracerebroventricular administration of GABA-A and GABA-B receptor antagonists attenuate feeding and sleep-like behavior induced by L-pipecolic acid in the neonatal chick, J. Neurosci. Res. 73:270-275 https://doi.org/10.1002/jnr.10656
  38. Tamir, H. and S. Ratner. 1963, Enzymes of arginine metabolism in chicks, Arch. Biochem. Biophys. 102:249-258 https://doi.org/10.1016/0003-9861(63)90178-4
  39. Tomonaga, S., T. Tachibana, T. Takagi, E.-S. Saito, R. Zhang, D. M. Denbow and M. Furuse. 2004, Effect of central administration of carnosine and its constituents on behaviors in chicks, Brain Res. Bull. 63:75-82 https://doi.org/10.1016/j.brainresbull.2004.01.002
  40. van Luijtelaar, E. L. J. M., C. P. M. van der Grinten, H. J. Blokhuis and A. M. Coenen. 1987, Sleep in the domestic hen (Gallus domesticus), Physiol. Behav. 41:409-414 https://doi.org/10.1016/0031-9384(87)90074-6
  41. Watson, G. S., J. T. Roach and K. J. Sufka. 1999, Benzodiazepine receptor function in the chick social separation-stress procedure, Exp. Clin. Psychopharmacol. 7:83-89 https://doi.org/10.1037/1064-1297.7.2.83
  42. Wolosker, H., S. Blackshaw and S. H. Snyder. 1999, Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission, Proc. Natl. Acad. Sci. USA. 96:13409-13414 https://doi.org/10.1073/pnas.96.23.13409
  43. Wright, B., A. H. Lacchini, A. J. Davies and A. J. Walker. 2006, Regulation of nitric oxide production in snail (Lymnaea stagnalis) defence cells: a role for PKC and ERK signalling pathways, Biol. Cell 98:265-278 https://doi.org/10.1042/BC20050066
  44. Yamane, H., Y. Tsuneyoshi, D. M. Denbow, M. Furuse. 2009, NMethyl- D-aspartate and α-amino-3-hydroxy-5-methyl-4- isoxazolepropionate receptors involved in the induction of sedative effects under an acute stress in neonatal chicks, Amino Acids, in press
  45. Yudkoff, M. 1999. Diseases of amino acid metabolism. In: Basic Neurochemistry. Molecular, cellular and medical aspects (Ed. G. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher and M. D. Uhler). Sixth Edition. pp. 887-915, Lippincott-Raven Publishers. New York
  46. Zomkowski, A. D. E., A. R. S. Santos and A. L. S. Rodrigues. 2006, Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice, Prog. Neuropsychopharmacol. Biol. Psychiatry 30:1419-1425 https://doi.org/10.1016/j.pnpbp.2006.05.016

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