대한수의학회지 (Korean Journal of Veterinary Research)

  • 제49권4호
  • /
  • Pages.365-368
  • /
  • 2009
  • /
  • 2466-1384(pISSN)
  • /
  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
권호 표지

Hyperinsulinism in a dog with beta-cell neoplasia (insulinoma)

  • Yu, Do-Hyeon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Jong-Hyun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Song, Ru-Hui (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Noh, Dong-Ho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Li, Ying-Hua (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Mi-Jin (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Cho, Ara (Department of Veterinary Pathology, College of Veterinary Medicine,Chonbuk National University) ;
  • Kim, Bumseok (Department of Veterinary Pathology, College of Veterinary Medicine,Chonbuk National University) ;
  • Park, Jinho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University)
  • 심사 : 2009.10.22
  • 발행 : 2009.12.31
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초록

A six-year-old female cocker spaniel presented with recurring episodes of pelvic limb weakness and intermittent seizures. Laboratory analysis revealed marked hypoglycemia and an elevated serum insulin concentration. A pancreatic beta-cell tumor at stage III ($T_1N_1M_1$) was diagnosed based on serial blood glucose and insulin measurements along with diagnostic imaging. The patient survived for 140 days after diagnosis with medical management, including frequent feeding and prednisolone therapy. On necropsy, necrosis and masses in the peripancreatic omentum and liver were found; pancreatic beta-cell neoplasia with metastasis to the liver was confirmed by histopathologic examination. This case reports hyper-insulinism in a dog presenting with hypoglycemic seizures.

키워드

참고문헌

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