Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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A Nationwide Survey on the Prevalence of Intestinal Parasitic Infections in the Republic of Korea, 2004

  • Kim, Tong-Soo (Department of Malaria and Parasitic diseases, National Institute of Health) ;
  • Cho, Shin-Hyeong (Department of Malaria and Parasitic diseases, National Institute of Health) ;
  • Huh, Sun (Department of Parasitology, Hallym University College of Medicine) ;
  • Kong, Yoon (Department of Molecular parasitology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine) ;
  • Sohn, Woon-Mok (Department of Parasitology, Institute of Health Sciences, Gyeongsang National University College of Medicine) ;
  • Hwang, Seung-Sik (Department of Social and Preventive Medicine, Inha University School of Medicine) ;
  • Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center) ;
  • Lee, Soon-Hyung (Korea Association of Health Promotion) ;
  • Park, Yun-Kyu (Department of Parasitology, Inha University School of Medicine) ;
  • Oh, Dae-Kyu (Centers for Disease Control and Prevention) ;
  • Lee, Jong-Koo (Centers for Disease Control and Prevention) ;
  • Working Groups in National Institute of Health, Working Groups in National Institute of Health (Working Groups in National Institute of Health) ;
  • Korea Association of Health Promotion, Korea Association of Health Promotion (Korea Association of Health Promotion)
  • Published : 2009.03.31
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Abstract

National surveys on the prevalence of intestinal parasitic infections have been carried out every 5-7 years since 1971 in the Republic of Korea in order to establish control measures. The present nationwide survey was conducted from June to December 2004. The 10% population sampling data of Population and Housing Census by the Korean government in 2000 was used as the survey population. One sample was selected randomly from each of the 22,858 registered subjects, and a total of 20,541 people were ultimately included in this survey. Fecal examinations were performed by the cellophane thick smear and saturated brine flotation techniques. Pinworm infection was examined by cello-tape anal swab method. This survey also included a questionnaire study for a socioeconomic analysis. The total helminth egg positive rate was 3.7%, and the estimated total positive number among nationwide people was 1,780,000. The rates in urban and rural areas were 3.1% and 6.8%, respectively. As the total egg positive rate in the 6th survey in 1997 was 2.4%, the present survey showed that there was a considerable degree of increase in the prevalence rate of intestinal parasitic infections over the 7-year period following the 6th survey. The largest increases occurred in the egg positive rates of Clonorchis sinensis and heterophyids including Metagonimus yokogawai.

Keywords

References

  1. Seo BS, Rim HJ, Loh IK, Lee SH, Cho SY, Park SC, Bae JW, Kim JH, Lee JS, Koo BY, Kim KS. Study on the status of helminthic infections in Koreans. Korean J Parasitol 1969; 7: 53-70 https://doi.org/10.3347/kjp.1969.7.1.53
  2. Kim CH, Park CH, Kim HJ, Chun HB, Min HK, Koh TY, Soh CT. Prevalence of intestinal parasites in Korea. Korean J Parasitol 1971;9: 25-38 https://doi.org/10.3347/kjp.1971.9.1.25
  3. Ministry of Health and Welfare, Korea Association of Health Promotion. Prevalence of intestinal parasitic infection in Korea-the sixth and the 7th reports-. Seoul, Korea. 1997 (6th) & 2004 (7th)
  4. Kim BJ, Ock MS, Kim IS, Yeo UB. Infection status of Clonorchis sinensis in residents of Hamyang-gun, Gyeongsangnam-do, Korea. Korean J Parasitol 2002; 40: 191-193 https://doi.org/10.3347/kjp.2002.40.4.191
  5. Lee GS, Cho IS, Lee YH, Noh HJ, Shin DW, Lee SG, Lee TY. Epidemiological study of clonorchiasis and metagonimiasis along the Geum-gang (River) in Okcheon-gun (county), Korea. Korean J Parasitol 2002; 40: 9-16 https://doi.org/10.3347/kjp.2002.40.1.9
  6. Choi DW, Park SD, Kim JW, Ahn DH, Kim YM. Intestinal parasite survey of Kyungbook National University Hospital patients. Korean J Parasitol 1971; 9: 47-53 https://doi.org/10.3347/kjp.1971.9.2.47
  7. Min DY, Ahn MH, Kim KM, Kim CW. Intestinal parasite survey in Seoul by stool examination at Hanyang University Hospital. Korean J Parasitol 1986; 24: 209-212 https://doi.org/10.3347/kjp.1986.24.2.209
  8. Chai JY, Han ET, Park YK, Guk SM, Kim JL, Lee SH. High endemicity of Metagonimus yokogawai infection among residents of Samchokshi, Kangwon-do. Korean J Parasitol 2000; 38: 33-36 https://doi.org/10.3347/kjp.2000.38.1.33
  9. Kim CH, Na YE, Kim NM, Shin DW, Chang DY. Intestinal parasite and Clonorchis sinensis infection among the inhabitants in the upper stream of Taechong Dam, Kumgang (River). Korean J Parasitol 1994; 32: 207-214 https://doi.org/10.3347/kjp.1994.32.4.207
  10. Kim DG, Kim TS, Cho SH, Song HJ, Sohn WM. Heterophyid metacercarial infections in brackish water fishes from Jinju-man (Bay), Kyongsangnam-do, Korea. Korean J Parasitol 2006; 44: 7-13 https://doi.org/10.3347/kjp.2006.44.1.7
  11. Chai JY, Park JH, Han ET, Shin EH, Kim JL, Guk SM, Hong KS, Lee SH, Rim HJ. Prevalence of Heterophyes nocens and Pygydiopsis summa infections among residents of the western and southern coastal islands of the Republic of Korea. Am J Trop Med Hyg 2004; 71: 617-622
  12. Cochran WG. Sampling Techniques. John Wiley & Sons, Inc. 1977
  13. Newcombe RG. Two-sided confidence intervals for the single proportion:Comparison of seven methods. Statist Med 1998; 17:857-872 https://doi.org/10.1002/(SICI)1097-0258(19980430)17:8<857::AID-SIM777>3.0.CO;2-E
  14. Agresti A. An introduction to categorical data analysis. John Wiley & Sons, Inc. 1996
  15. Agresti A, Coull BA. Approximate is better than 'Exact' for interval estimation of Binomial proportions. Am Statist 1998; 52: 119-126 https://doi.org/10.2307/2685469
  16. SAS. SAS/STAT$^{\circledR}$ User’s Guide (version 6.4th ed.). Cary, NC. SAS Inst. Inc. 1989
  17. SPSS. User’s Guide (version 12.0.1). Chicago, Illinois USA. SPSS Inc. 1990
  18. Parrish RS, Ware GO, Field JE. Slope ratio assay using SAS. Proc. SAS User's Group Int 1980; pp 429-437
  19. Hong ST, Chai JY, Choi MH, Huh S, Rim HJ, Lee SH. A successful experience of soil-transmitted helminth control in the Republic of Korea. Korean J Parasitol 2006; 44: 177-185 https://doi.org/10.3347/kjp.2006.44.3.177
  20. Seo BS, Lee SH, Cho SY. An epidemiologic study on clonorchiasis and metagonimiasis in riverside areas in Korea. Korean J Parasitol 1981; 19: 137-150 https://doi.org/10.3347/kjp.1981.19.2.137
  21. Cho SH, Lee KY, Lee BC, Cho PY, Cheun HI, Hong ST, Sohn WM, Kim TS. Prevalence of clonorchiasis in southern endemic areas of Korea in 2006. Korean J Parasitol 2008; 46: 133-137 https://doi.org/10.3347/kjp.2008.46.3.133

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  19. A Survey of Intestinal Parasite Infection during a 10-Year Period (2003-2012) vol.16, pp.3, 2009, https://doi.org/10.5145/acm.2013.16.3.134
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  26. Control of clonorchiasis in Korea: effectiveness of health education for community leaders and individuals in an endemic area vol.19, pp.9, 2009, https://doi.org/10.1111/tmi.12338
  27. Anomalous union of the pancreaticobiliary duct without choledochal cyst: is cholecystectomy alone sufficient? vol.399, pp.8, 2014, https://doi.org/10.1007/s00423-014-1223-5
  28. Risk factors for perihilar cholangiocarcinoma: A hospital‐based case–control study vol.35, pp.3, 2009, https://doi.org/10.1111/liv.12618
  29. Evaluation of Modified Formalin-Ether Concentration Method Using Para Tube in Clinical Settings vol.35, pp.4, 2015, https://doi.org/10.3343/alm.2015.35.4.445
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  38. Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target vol.18, pp.3, 2009, https://doi.org/10.3390/ijms18030557
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