Abstract
The study found out developmental factors of the liver diseases in 29, 531 cases of the healthy adults who were diagnosed by using ultrasound at domestic healthcare centers in 6 cities. The results are as follows. Based on the result of the study, the liver diseases diagnosed by using ultrasound was revealed to show 43.1% of prevalence, and the occurrence was significantly higher in male (23.3%) than in female (19.8%). The prevalence of hepatic diseases related to the BMI was revealed to show highest prevalence of the fatty liver in obese group (BMI $\geqq$ 25) by recording 44.3%. Smoking contributed to the high prevalence of all liver diseases. Although the fatty liver was the most frequently occurred form of liver diseases by recording the prevalence of 49.1% (22.2% in male, 26.9% in female), the significant difference was found only in female (p < 0.05), but male group did not show significant difference (p > 0.05). The prevalence of hepatic diseases related to the hypertension was revealed to show highest prevalence of the fatty liver in hypertension group by recording 67.7%. The prevalence of hepatic diseases related to the diabetes was revealed to show highest prevalence of the fatty liver in diabetes group by recording 66.2%. The high prevalence of all hepatic diseases was related to diabetes mellitus with statistical significance (p < 0.001). The multiple regression analysis for the related factors which affect the prevalence of the liver diseases showed the higher prevalence by age. Sex, obesity and diabetes mellitus were positively related to the prevalence (p < 0.05) while hypertension and smoking showed no significant relationship to the prevalence of the disease (p > 0.05).
전국 6개 도시의 종합건강검진센터에서 검진을 받은 건강한 성인 총 수진자 29, 531명을 대상으로 복부초음파검사로 진단된 간질환의 건강관련 요인을 분석한 결론은 다음과 같다. 초음파로 진단된 간질환 유병률은 43.1%로 나타났고, 성별로는 남성에서 23.3%, 여성에서 19.8%로 남성에게서 유의하게 높게 나타났으며(p < 0.001), BMI에 따른 유병률은 BMI $\geqq$ 25인 비만 군에서 지방간만이 44.3%로 높은 유병률로 나타났으며 이는 통계적으로 유의하게 나타났다(p < 0.001). 흡연에 따른 유병률은 흡연자군에서 지방간이 49.1%(남성 22.2%, 여성 26.9%)로 가장 높게 나타났고, 통계적으로 여성에서는 유의한 차이가 있는 것으로 나타났으며(p < 0.05), 남성은 유의한 차이가 없는 것으로 나타났다(p > 0.05). 고혈압에 따른 유병률은 정상군에서 지방간이 67.7%로 가장 높은 유병률로 나타났고, 당뇨에 따른 유병률은 당뇨 군에서 전체 간질환이 높게 나타났으며 지방간이 66.2%로 가장 높게 유병률로 나타났다(p < 0.001). 간질환 유병률에 대한 다중회귀분석 결과는 연령이 증가할수록 발병가능성이 높게 나타났고, 연령, 성별, 비만도, 당뇨는 유병률과 연관성이 있게 나타났으나(p < 0.05), 고혈압과 흡연에서는 유의성이 없는 것으로 나타났다(p > 0.05).