The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Antioxidant Activities and the Effect of Reducing Serum Alcohol Concentration of Lentinus edodes

표고버섯의 항산화능과 알코올분해능에 미치는 영향

  • Kim, Chae-Hyun (Department of Herbology, College of Oriental Medicine, Dongshin University) ;
  • Jeong, Jong-Gil (Department of Herbology, College of Oriental Medicine, Dongshin University)
  • 김재현 (동신대학교 한의과대학 본초학교실) ;
  • 정종길 (동신대학교 한의과대학 본초학교실)
  • Published : 2009.12.30
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Abstract

Objectives : The purpose of this study is to evaluate antioxidant activities and reducing serum alcohol concentration of extract of Lentinus edodes on the alcohol administered rats. Methods : Antioxidant effect was measured by total phenolic compound and DPPH-radical scavenging activity of extract of Lentinus edodes in vitro. Blood alcohol concentration, aldehyde concentration, malondialdehyde concentration, glutathion concentration were measured in vivo. Results : The extract of Lentinus edodes increased DPPH-radical scavenging activity dose-dependently. The water extract with boiling water showed lower antioxidant activity and phenolic content than 70% ethanol extract in vitro. Blood alcohol concentration was significantly reduced by pre-treatment of ethanol extract of Lentinus edodes. The effect was more significant than commercial product used as a positive control. Conclusions : This study suggest that Lentinus edodes can be a potential nature resource for the management of ethanol toxicity although the mechanism of action involved in the treatment remains to be explored.

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