Retrospective Drugs Utilization Review Study for Chronic Kidney Disease Using National Health Insurance Database

건강보험 자료를 이용한 만성신부전 환자의 신독성 약물사용 현황

  • Kim, Dong-Sook (Department of Research, Health Insurance Review & Assessment Service) ;
  • Lee, Hyun-Jeong (Department of Research, Health Insurance Review & Assessment Service) ;
  • Son, In-Ja (Pharmacy Departement, Seoul National University Hospital) ;
  • Kim, Gui-Sook (Pharmacy Departement, Seoul National University Hospital) ;
  • Shin, Joo-Young (Departement of Preventive Medicine, College of Medicine, Seoul National University) ;
  • Lee, Kun-Sei (Department of Research, Health Insurance Review & Assessment Service)
  • 김동숙 (건강보험심사평가원 심사평가연구실) ;
  • 이현정 (건강보험심사평가원 심사평가연구실) ;
  • 손인자 (서울대학교병원 약제부) ;
  • 김귀숙 (서울대학교병원 약제부) ;
  • 신주영 (서울대학교 의과대학 약물역학교실) ;
  • 이건세 (건강보험심사평가원 심사평가연구실)
  • Published : 2009.06.30

Abstract

The purpose was to implement drug utilization review (DUR) for whom were diagnosed with chronic kidney disease (CKD) population using health insurance claim data. This study constructed drug utilization database using Health Insurance Review and Assessment Service (HIRA) database and selected contraindicated drugs with kidney based on previously developed drug utilization guide and reviewing other countries' examples. Main outcome measures were the proportion of prescription for 1 or more drugs of concern. The cohort included 115,948 subjects, who were diagnosed with chronic kidney disease. Inappropriate drugs with CKD patients was some used, and the most commonly prescribed classes were aluminum drugs. However it is difficult to find problems with inappropriate drug because claims data doesn't have laboratory data. Based on the result of retrospective drug utilization review study, more studies should be analysed drug utilization patterns and monitoring system should be developed.

Keywords

References

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