루프스 신염 치료로 Cyclosporine 투여 후 발생한 가역성후백질뇌병증 증후군

A case of Reversible Posterior Leukoencephalopathy Syndrome in Lupus Nephritis Treated with Cyclosporine

  • 나상준 (건양대학교 의과대학 신경과학교실) ;
  • 이기욱 (건양대학교 의과대학 신경과학교실)
  • Na, Sang-Jun (Department of Neurology, Konyang University College of Medicine) ;
  • Lee, Kee-Ook (Department of Neurology, Konyang University College of Medicine)
  • 투고 : 2008.05.27
  • 심사 : 2008.11.25
  • 발행 : 2009.06.30

초록

Reversible posterior leukoencephalopathy syndrome (RPLS) is an acute encephalopathy, usually characterized by seizures, visual disorder, mental change and reversible posterior white and gray matter lesions on brain magnetic resonance imaging (MRI). Conditions commonly associated with RPLS include acute renal failure, eclampsia, hypertension, immunosuppresion state, and use of intravenous immunoglobulin or chemotherapy, and additional contributing factors. We report the case of RPLS associated with cyclosporine use in lupus nephritis. In this case, it was not clearly elucidated which was main cause of RPLS. We could think RPLS developed maybe due to combined effect of cyclosporine and lupus nephritis.

키워드

참고문헌

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