DOI QR코드

DOI QR Code

Preparation and Characteristics of Bread by Medicinal Herb Composites with Cognitive Function

인지기능활성을 가진 생약복합물을 이용한 빵의 제조 및 특성

  • Kang, Jin-Soon (School of Food Science, International University of Korea) ;
  • Kang, Shin-Kwon (School of Food Science, International University of Korea) ;
  • Kim, Hee-Suk (School of Food Science, International University of Korea)
  • 강진순 (한국국제대학교 식품과학부) ;
  • 강신권 (한국국제대학교 식품과학부) ;
  • 김희숙 (한국국제대학교 식품과학부)
  • Published : 2009.09.30

Abstract

In this study, the breads with medicinal herbs (MH) composites showing cognitive function were prepared and their characteristics were examined. Fifteen kinds of medicinal herbs were extracted with hot water and divided into 3 groups (MH-1, MH-2, MH-3) based on their contents. All groups showed cognitive function in terms of promoting muscarinic receptor, NMDA receptor and acetylcholinesterase inhibition. In the preparation of breads containing MH extracts of various contents (0, 10, 20, 30, and 50%), there were no significant difference among loaf weight of all groups, but loaf volume of all groups were significantly (p<0.05) decreased with increasing content of MH extracts compared to the control group. The "a" and "b" values of bread crumb increased with the content of MH extracts while "L" value decreased, but these values of bread crust were similar to the control group. The most improvements in hardness, fracturability, cohesiveness, gumminess and chewiness of bread were noticed by the addition of 10$\sim$20% MH extracts, while adhesiveness and springiness of bread were the most by the 30% addition ones. Through the sensory evaluation, it was revealed that appearance, mouth feeling, taste, overall preference and crumb texture of bread were not significantly different (p<0.05) between control and those with the 10% addition ones. Therefore the 10% addition ones, which got similar scores to control, will make the most desirable product.

생약 추출물의 기능성 소재로서 이용 가능성을 조사하고자 황련, 복분자, 하수오, 산약, 산수유, 치자엽, 당귀, 작약, 창출, 저령, 시호, 천궁, 택사, 삼백초, 백복령 등을 이용하여 인지기능 활성 실험을 수행한 결과 MH-1, MH-2 및 MH-3은 인지기능의 지표가 되는 M1 binding site 저해, glycine binding site 저해 및 AChE 저해활성 등에서 유의성 또는 높은 활성을 보였기 때문에 기능성식품 제조를 위한 퇴행성 뇌질환자의 뇌세포 활성 촉진 및 퇴화 예방과 조절을 위한 인지기능 증강 소재로의 활용가치가 있음이 증명됨에 따라 인지기능 증진 빵 제조에 활용하였다. 이와 같이 생약재의 인지기능 활성능을 확인한 후 활성이 높은 위의 생약 열수추출물을 일정한 비율로(밀가루를 기준으로 추출물은 10%, 20%, 30%, 50%) 첨가하여 식빵을 배합하였다. 제빵적성은 빵의 용적과 조직감을 측정하고 관능검사를 통하여 판정하였다. 빵의 용적은 생약추출물을 첨가하여 만든 빵의 경우 전체적으로 대조군보다 감소하였으나 추출물 20% 첨가 시에는 빵의 비용적에서 대조군과 별 차이를 인식할 수 없었다. 빵의 조직감은 추출물의 첨가량이 증가할수록 경도, 점착성, 씹힘성이 대조군에 비해 증가하였으며 부서짐성에서는 감소하였고 탄력성, 응집성, 복원성은 큰 변화가 없었다. 생약 추출물의 첨가에 따라 빵의 crumb색은 어두워졌으며 생약 추출물 첨가량과 관능검사와의 관계는 첨가량이 증가 할수록 맛, 향미, 전체적인 선호도, 입안에서의 느낌이 유의적으로 낮은 경향을 보였다. 따라서 전체적으로 대조군과 유사하게 좋은 점수를 얻은 추출물 10% 첨가 빵이 제품으로 생산되었을 때가 가장 적합한 것으로 나타났다.

Keywords

References

  1. Alfredo AS. 1988. Assessing vision in patients with Alzheimer,s disease. West J Med 148: 693
  2. Ball MJ, Fisman M, Hachinski V, Blume W, Fox A, Kral A, Kirshen AJ, Fox H, Merskey H. 1985. A new definition of Alzheimer,s disease: a hippocampal dementia. Lancet 8419: 14-16
  3. Korea Institute and Social Affairs. 2007
  4. Cheon YH, Chang YK, Baik TK. 1999. Evidence of memory improvement by phosphatidyl choline supplement at fetus and neonate. Kor J Nutr 32: 864-869
  5. Leathwood PD, Heck E, Mauron J. 1982. Phosphatidyl choline and avoidance performance in 17 month-old SEC/1ReJ mice. Life Sci 30: 1065-1071 https://doi.org/10.1016/0024-3205(82)90526-4
  6. Israel M, Lesbats B, Morel N, Manaranche R, Salle GLGI. 1998. Is the acetylcholine releasing protein mediatophore present in rat brain? REBS Letter 233: 412-426
  7. Wang Y, Kikuchi T, Sakai J, Wu L, Sato K, Okumura F. 1999. Aged-related modifications of effects of ketamine and propofol on rat hippocampal acetylcholine release studied by in vivo brain microdialysis. Acta Anaesthsiol Scand 44: 112-117 https://doi.org/10.1034/j.1399-6576.2000.440120.x
  8. Ellman GL, Coutney KD, Andres V, Featherstone RM. 1961. A new and rapid colorimetric determination acethylcholinesterase activity. Biochem Pharmacol 7: 88-95 https://doi.org/10.1016/0006-2952(61)90145-9
  9. Kim LY. 2001. Effect of wheat germ powder on the quality of white bread. MS Thesis. Suncheon National University, Jeonnam, Korea
  10. SAS Institute, Inc. 1988. SAS/STAT user's guide version 6.03. Statistical analysis systems institute, Cary, NC, USA
  11. Kim YS, Kim JS, Kim SK, Heor JH, Lee BE, Ryu SY. 2001. Binding affinity of some herbal extracts on the muscarinis acetylcholine receptor subtype 1 $(mAChR-M_1)$. Kor J Pharmacogn 32: 219-225
  12. Levey AL. 1996. Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease. Proc Natl Acad Sci USA 93: 12641- 12646
  13. Messer WS Jr, Rajeswaran WG, Cao Y, Zhang HJ, el-Assadi AA, Dockery C, Liske J, O'Brien J, Williams FE, Huang XP, Wroblewski ME, Nagy PI, Peseckis SM. 2000. Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors. Pharm Acta Helv 74: 135-140 https://doi.org/10.1016/S0031-6865(99)00026-6
  14. Lee IO. 2008. NMDA receptor channel. Hanyang Med Rev 28: 17-27
  15. Kim JS, Kim YS, Kim SK, Heor JH, Lee BH, Choi BW, Ryu GS, Park EK, Zee OP, Ryu SY. 2002. Inhibitory effects of some herbal extracts on the acethylcholinesterase (AChE) in vitro. Kor J Pharmacogn 33: 211-218
  16. Schmeller T, Latz-Bruning B, Mink M. 1997. Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivotes. Phytochemistry 44: 257-266 https://doi.org/10.1016/S0031-9422(96)00545-6
  17. Wang W, Chen K, Guan Y. 1999. Effect of berberine hydrochloride on muscarinic receptors. Acta Pharmaceutica Sinica 34: 260-263
  18. Lee MR, Sun BS, Gu LJ, Wang CY, Fang ZM, Zhen Wang, Mo EK, Ly SY, Sung CK. 2009. Effects of the deer antler extract on scopolamine-induced memory impairment and its related enzyme activities. J Korean Soc Food Sci Nutr 38: 409-414 https://doi.org/10.3746/jkfn.2009.38.4.409
  19. Lee SY, Choi JS, Choi MO, Cho SH, Kim KBWR, Lee WH, Park SM, Ahn DH. 2006. Effect of extracts from Glycyorrhiza uralensis and Curcula longa on shelf-life and quality of bread. J Korean Soc Food Sci Nutr 35: 912-918 https://doi.org/10.3746/jkfn.2006.35.7.912
  20. Kim EJ, Kim SM. 1998. Bread properties utilizing extracts of pine needle according to preparation method. J Korean Food Sci Technol 30: 542-547
  21. Chung HC, Lee JT, Kwon OJ. 2004. Bread properties utilizing extracts of Ganoderma lucidum. J Korean Soc Food Sci Nutr 33: 1201-1205 https://doi.org/10.3746/jkfn.2004.33.7.1201
  22. Kim YA. 2005. Effects of Lycium chinense powders on the quality characteristics of yellow layer cake. J Korean Soc Food Sci Nutr 34: 403-407 https://doi.org/10.3746/jkfn.2005.34.3.403
  23. Kim JY. 2002. Effects of chitosan in shelf-life and quality of bread. MS Thesis. Pukyong National University, Busan, Korea
  24. Bowers J. 1992. Food theory and applications. Macmillan, New York, USA. Vol 2, p 326
  25. Bae JH, Woo HS, Choi HJ, Choi C. 2001. Qualities of bread added with Korean persimmon leaf powder. J Korean Soc Food Sci Nutr 30: 882-88
  26. Ryu HS, Kim HS. 2006. Effect of Zingiber officinale and Hizikia fusiforme water extracts on NO production in macrophage of mice. Korean J Food Nutr 19: 327-331
  27. Choi OJ, Kim YD, Kang SK, Jung HS, Ko MS, Lee HC. 1999. Properties on the quality characteristics of bread added with Angelica keiskei Koidz flour. J Korean Soc Food Sci Nutr 28: 118-125
  28. Hwang YK, Hyun YH, Lee YS. 2001. Study on the characteristic of bread with green tea powder. Korean J Food Nutr 14: 311-316
  29. Kweon MK, Jeon SW, Kim DS. 2003. Quality characteristics of sponge cake with addition of laver powder. J Korean Soc Food Sci Nutr 32: 1278-1284 https://doi.org/10.3746/jkfn.2003.32.8.1278
  30. Chabot JF. 1979. Preparation of food science sample for SEM. Scanning Electron Microscopy 3: 279-286
  31. Jeong CH, Shim KH. 2004. Quality characteristics of sponge cakes with addition of Pleurotus eryngii mushroom powder. J Korean Soc Food Sci Nutr 33: 716-722 https://doi.org/10.3746/jkfn.2004.33.4.716
  32. Yi SY, Kim CS, Song YS, Park JH. 2001. Studies on the quality characteristics of sponge cakes with addition of yam powder. J Korean Soc Food Sci Nutr 30: 48-55
  33. Chun SS. 2003. Development of functional sponge cakes with onion powder. J Korean Soc Food Sci Nutr 32: 62-66 https://doi.org/10.3746/jkfn.2003.32.1.062

Cited by

  1. Effect of Autoclave and Microwave Treatments on Quality of Bread vol.41, pp.5, 2012, https://doi.org/10.3746/jkfn.2012.41.5.681
  2. Preparation and Characteristics of Soy Milk Jelly using Medicinal Herb Composites with Cognitive Effects vol.41, pp.9, 2012, https://doi.org/10.3746/jkfn.2012.41.9.1281
  3. Neuroprotective Effects of Bread Containing Cirsium setidens or Aster scaber vol.43, pp.6, 2014, https://doi.org/10.3746/jkfn.2014.43.6.829
  4. Evaluation of Physicochemical Properties and Biological Activities of Steamed and Fermented Deodeok (Codonopsis lanceolata) vol.44, pp.1, 2012, https://doi.org/10.9721/KJFST.2012.44.1.135
  5. Enhancement of Antioxidative Activity of Codonopsis lanceolata by Stepwise Steaming Process vol.20, pp.4, 2012, https://doi.org/10.7783/KJMCS.2012.20.4.238
  6. 황련(Coptis Radix)으로부터 분리된 물질의 항균효능 및 화장품 약리활성에 대한 연구 vol.34, pp.2, 2017, https://doi.org/10.12925/jkocs.2017.34.2.271