Journal of Evidence-Based Herbal Medicine

The Korean Society of Oriental Pharmacy (대한한약학회)
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Inhibitory effect of Butanol fraction of Ecklonia cava on inflammatory mediators in RAW 264.7 cells

  • Chae, Hee-Sung (College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Wonkwang University) ;
  • Choi, Jang-Ki (College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Wonkwang University) ;
  • Kwon, Dong-Yeul (College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Wonkwang University)
  • Published : 2009.06.30
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Abstract

Objectives : The purpose of this study was to investigate the anti-inflammatory effects of Ecklonia cava butanol extract (BFEC) on RAW 264.7 cells. Method : To evaluate of anti-inflammatory of BFEC, We examined cytokine and Nitric oxide(NO) production in lipopolysacchride (LPS)-induced RAW 264.7 cell. Result : Extract of BFEC inhibit LPS-induced interleukin (IL)-6, NO production in human monocyte RAW 264.7 cells. Conclusion : BFEC down-regulated LPS-induced IL-6, NO production, which may be provide a clinical basis for anti-inflammatory properities of BFEC.

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