Journal of Pharmaceutical Investigation

The Korean Society of Pharmaceutical Sciences and Technology (한국약제학회)
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Pharmaceutical Devices for Oral Cavity-based Local and Systemic Drug Delivery

  • Yun, Gyi-Ae (Department of Food Science and Technology, Chung-Ang University) ;
  • Choi, Sung-Up (Division of Pharmaceutics, College of Pharmacy, Chung-Ang University) ;
  • Park, Ki-Hwan (Department of Food Science and Technology, Chung-Ang University) ;
  • Rhee, Yun-Seok (School of Pharmacy, Sungkyunkwan University) ;
  • Lee, Beom-Jin (Bioavailability Control Laboratory, College of Pharmacy, Kangwon National University) ;
  • Lee, Jae-Hwi (Division of Pharmaceutics, College of Pharmacy, Chung-Ang University)
  • Received : 2010.08.24
  • Accepted : 2010.10.07
  • Published : 2010.12.20
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Abstract

Pharmaceutical technology has primarily focused on the development of the best dosage forms depending on the route of administration. The design of dosage forms is greatly influenced by the route of administration. Due to a variety of advantages such as avoidance of first-pass effect, abundant blood supply and easy access to the absorption site, the oral cavity has frequently been selected as a site for drug delivery. Since the oral cavity is relatively unique from the anatomical and physiological viewpoint, one should always consider these conditions when designing the drug delivery systems for the oral cavity. In this regard, the current review paper was prepared to summarize the essential features of the drug delivery systems utilized in the oral cavity, along with the introduction of various dosage forms developed to date.

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References

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