Journal of Korean Medicine Rehabilitation (한방재활의학과학회지)

The society of Korean Medicine Rehabilitation (한방재활의학과학회)
권호 표지

The Study on Association between Abdominal Visceral Fat and Obesity Indices in Obese Adult

비만 성인에서 복부 내장지방과 단순 비만 지표와의 연관성 연구

  • Yoo, Jin-Sook (Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Song, Yun-Kyung (Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Lim, Hyung-Ho (Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Kyung-Won University)
  • 유진숙 (경원대학교 한의과대학 한방재활의학과교실) ;
  • 송윤경 (경원대학교 한의과대학 한방재활의학과교실) ;
  • 임형호 (경원대학교 한의과대학 한방재활의학과교실)
  • Received : 2010.03.22
  • Accepted : 2010.04.05
  • Published : 2010.04.30
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Abstract

Objectives : This study examined search on how the obesity indices, that are largely used in clinics such as waist circumference(WC), body mass index(BMI) and waist-hip ratio(WHR), are related to the visceral fat that was measured from abdominal computed tomography(CT) and the ratio of visceral fat/subcutaneous fat. Then, two groups ware compared in order to find out which characteristics of ordinary adults relationship with the abdominal obesity. Two groups are divided as follows; ones who are obese based on the measurement of WC and the others who are obese based on the level of BMI. Methods : A group of 63 test subjects that were gathered in the oriental medical hospital of Kyung-Won university is divided into two groups; ones (n=51, general obesity; group A) who have $BMI{\geq}25$ and $WC{\geq}85$, and the others (n=12, abdominal obesity; group B) who have BMI<25 and $WC{\geq}85$. Then, each group's obesity indices, abdominal CT, lipid level, glucose, adiponectin, leptin and C-reactive protein(CRP) are compared. In addition, subjects are again divided into two to examine the characteristics; ones (n=14, visceral obesity; group C) with visceral obesity based on the ratio between visceral fat and subcutaneous fat measured through abdominal CT, and the others (n=38, non-visceral obesity; group D) who are obese but not viscerally obese. Results & Conclusions : As a measurement that applies abdominal visceral fat and subcutaneous fat, BMI and WC can be considered as an appropriate obesity index while WHR cannot appropriately apply the abdominal fat amount. Moreover, the study indicates that abdominal obesity group based on the ratio of visceral fat/subcutaneous fat has more significant difference than the abdominal obesity group based on the WC in case of blood lipid index.

Keywords

Acknowledgement

Supported by : 경원대학교

References

  1. 한국보건사회연구원. 2007국민건강영양조사. 서울. 2008:56-7.
  2. Bouchard C, Bray GA, Hubbard VS. Basic and clinical aspects of regional fat distribution. Am J Clin Nutr. 1990;52:946-50.
  3. Kannel KB, Cupples LA, Ramasnami R, et al. Regional obesity and risk of cardiovascular disease. The Framingham Study. J Clin Epidemiol. 1991;44:183-90. https://doi.org/10.1016/0895-4356(91)90265-B
  4. Despres JP, Isabelle Lemieux, Jean Bergeron, Pilippe Pibarot, et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol. 2008;28:1039-49. https://doi.org/10.1161/ATVBAHA.107.159228
  5. Despres JP. The insulin resistance-dyslipidemic syndrome of visceral obesity: effect on patient's risk. Obes Res. 1998;6:8S-17S. https://doi.org/10.1002/j.1550-8528.1998.tb00683.x
  6. Jeamine B, Albu, Albert J, Kovera and Julia A, Johnson. Fat distribution and health in obesity. Ann of the New York academy of sciences. 2000;904:491-501.
  7. Matsuzawa Y. Pathophysiology and molecular mechanism of visceral fat syndrome: The Japanese Experience. Ann NY Aca Sci. 1987; 676:270-8.
  8. 이미선, 노호성. 내장형 비만과 피하지방형 비만여성에 대한 자전거 운동 및 회복시 지질대사의 변화 특성. 체육과학연구. 2005;16(2):64-73.
  9. 강재헌, 김경아, 조영규, 전정윤, 김옥현. 내장지방형 비만이 제2형 당뇨병 환자에게 미치는 영향에 관한 고찰. 대한비만학회지. 2006;15(4):175-86.
  10. Alberti KG, Zimmet P, Shaw J. The metabolic syndrome-a new worldwide definition. Lancet. 2005;366:1059-62. https://doi.org/10.1016/S0140-6736(05)67402-8
  11. 박혜순. 한국인에서의 대사증후군의 역학. 대한비만학회지. 2002;22:203-11.
  12. 이영미, 박혜순, 천병철, 김현수. 복부지방의 지표로서 부위별 허리둘레 측정값의 신뢰도. 대한비만학회지. 2002;11(2):123-30.
  13. Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S. Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism. 1987;36:54-9. https://doi.org/10.1016/0026-0495(87)90063-1
  14. 김선호, 고병희, 송일병. 사상체질분류검사지(QSCC)II의 표준화 연구-각 체질집단의 군집별 Profile분석을 중심으로. 사상의학회지. 1996;8(1):187-246.
  15. 이정찬, 고병희, 송일병. 사상체질분류검사지(QSCC)II의 타당성 연구-각 체질집단의 군집별 Profile분석을 중심으로. 사상의학회지. 1996;8(1):247-94.
  16. 박샛별, 연규월, 조성진. 비만 성인에서의 Adipokine발현과 정신사회적 요인. 대한비만학회지. 2005;14(2):82-93.
  17. 정병천, 박순홍, 이주영, 이신원, 정성창, 김정국, 하승우, 김보완. 제2형 당뇨병 환자에서의 비만 지수와 죽상경화증 위험인자들과의 상관성. 대한비만학회지. 2003;12(2):93-107.
  18. 이윤재, 황덕상, 이창훈, 이경섭. 피하지방 및 피하지방의 분획과 관련된 임상적 의의에 관한 고찰. 한방비만학회지. 2007;7(2):15-25.
  19. 김양현, 오상우, 김영성, 전중한, 양윤준, 윤영숙, 이언숙. 비만 여성의 복부지방 분포에 영향을 주는 요인. 대한비만학회지. 2005;14(1):39-46.
  20. 이아라, 정원석, 송미연. 폐경전 한국인 비만여성에서 복부지방의 분획별 특성에 대한 임상연구. 한방비만학회지. 2008;8(2):25-35.
  21. 김상만, 김성수, 윤수진, 심경원, 최희정, 김광민, 이득주. 복부 내장지방량을 가장 잘 표현할 수 있는 단순비만지표는?(체질량지수, 허리둘레, 허리엉덩이둘레비). 대한비만학회지. 1998;7(2):157-68.
  22. Mohan V, Vijayaprabha R, Rema M, Premalatha G, Poongothai S, Deepa R, et al. Clinical profile of lean NIDDM in South India. Diabetes Res Clin Prac. 1997;38:101-8. https://doi.org/10.1016/S0168-8227(97)00088-0
  23. Miyazaki Y, Mahankali A, Matsuda M, Mahankali S, Hardies J, Cusi K, et. al. Effects of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab. 2002;87:2784-91. https://doi.org/10.1210/jc.87.6.2784
  24. Nielsen S, Guo Z, Johnson CM, Hensrud DD, Jensen MD. Splanchnic lipolysis in humanobesity. J Clin Invest. 2004;113:1582-8. https://doi.org/10.1172/JCI21047
  25. Kelley DE, HUWE T, Goodpaster BH, et al. Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol Endocrinol Metab. 2000;279(5):941-8.
  26. Kettaneh A, Ducrimetier P, Chales Ma, et al. High plasma leptin predicts an increase in subcutaneous adiposity in children and adults. Eur J Clin Nutr. 2007;60(6):719-26.
  27. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001;86:1930-5. https://doi.org/10.1210/jc.86.5.1930
  28. Cnop M, Havel PJ, Utxchneider KM, Carr DB, Sinha MK, Boyko EJ, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia. 2003;46:459-69. https://doi.org/10.1007/s00125-003-1074-z
  29. Weltman A, Pritzlaff CJ, Wideman L, Considine RV, et al. Intensity of acute exercise does not affect serum leptin concentrations in young men. Med Sci Sports Exerc. 2000;32:1556-61.
  30. Ahina RS, Flier JS. Leptin. Ann Rev Physiology. 2000;62:413-37. https://doi.org/10.1146/annurev.physiol.62.1.413
  31. Sandoval DN, Davis SN. Leptin: metabolic control and regulation. J Diabetes Complications. 2003;17(2):108-13. https://doi.org/10.1016/S1056-8727(02)00167-8
  32. Iwahashi H, Funahashi T, Kurokawa N, Sayama K, Fukuda E, Okita K, et al. Plasma adiponectin levels in women with anorexia nervosa. Horm Metab Res. 2003;35(9):537-40. https://doi.org/10.1055/s-2003-42655
  33. 조영규, 강재헌. C-Reactive Protein과 심혈관질환의 예방. 대한비만학회지. 2006;15(2):81-90.