A Case Report of Chondroid Syringoma of Philtrum

인중에 발생한 연골모양 땀샘종의 치험례

  • Cha, Jeong Ho (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine) ;
  • Kim, Jin Woo (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine) ;
  • Shin, Han Kyung (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine) ;
  • Jung, Jae Hak (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine) ;
  • Kim, Young Hwan (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine) ;
  • Sun, Hook (Department of Plastic and Reconstructive Surgery, Baik Hospital, Inje University, School of Medicine)
  • 차정호 (인제대학교 의과대학 부산백병원 성형외과학교실) ;
  • 김진우 (인제대학교 의과대학 부산백병원 성형외과학교실) ;
  • 신한경 (인제대학교 의과대학 부산백병원 성형외과학교실) ;
  • 정재학 (인제대학교 의과대학 부산백병원 성형외과학교실) ;
  • 김영환 (인제대학교 의과대학 부산백병원 성형외과학교실) ;
  • 선욱 (인제대학교 의과대학 부산백병원 성형외과학교실)
  • Received : 2010.06.16
  • Accepted : 2010.09.10
  • Published : 2010.11.10

Abstract

Purpose: Chondroid syringoma is a rare mixed tumor of the skin that was first described by Hirsch and Helwig (1961). Characteristically, it is composed of the proliferation of epithelial cells in a myxoid and chondroid matrix. Most lesions occur on the head and neck region, and their size may range from 0.5~3 cm. Since a chondroid syringoma presents similar characteristics to other masses on the head and neck region, it is significantly important to distinguish with other masses by a surgical biopsy. Methods: A 51-year old woman presented with a painless nodular mass ($0.5{\times}0.5{\times}0.5cm$) on the philtrum, which appeared during the previous year. The mass was treated with a laser without a surgical biopsy. However, the size of the mass showed no changes. Surgical excision under local anesthesia was performed and sent for histopathology. Results: Gross examination showed a mass surrounded by a well developed capsule within the dermal layer. After complete excision without injury to the orbicularis oris muscle, the wound was covered with a local flap. The histology examination revealed numerous cuboid epithelial cells with tuboalveolar structures and keratinous cysts within a chondroid stroma. No recurrence or metastasis was observed at the follow-up visits. Conclusion: Chondroid syringoma is a rare mass on the face. An accurate diagnosis is essential for optimal treatment. This paper reports a case of a chondroid syringoma on the philtrum with a brief review of the relevant literature.

Keywords

References

  1. Hirsch P, Helwig EB: Chondroid syringoma: mixed tumor of skin, salivary gland type. Arch Dermatol 84: 835, 1961 https://doi.org/10.1001/archderm.1961.01580170129018
  2. Yavuzer R, Basterzi Y, Sari A, Bir F, Sezer C: Chondroid syringoma: A diagnosis more frequent than expected. Dermatol Surg 29: 179, 2003 https://doi.org/10.1046/j.1524-4725.2003.29045.x
  3. David E, Elenitsas R, Jaworky C, Johnson B: Lever's Histopathology of the Skin. 8th ed., Philadelphia, New York, Lippincott-Raven, 1996, p 789
  4. Ishimura E, Iwamoto H, Kobashi Y, Yamabe H, Ichijama K: Malignant chondroid syringoma: report of a case with widespread metastasis and review of pertinent literature. Cancer 52: 1966, 1983 https://doi.org/10.1002/1097-0142(19831115)52:10<1966::AID-CNCR2820521032>3.0.CO;2-7
  5. Monica B. Constantinescu, Jessica B. Chan, David S. Cassarino: Chondroid syringoma with tyrosine crystal: Case report and review of the literature. Am J Dermatopathol 32: 171, 2010 https://doi.org/10.1097/DAD.0b013e3181aec131
  6. Dominguez Iglesias F, Fresno Forcelledo F, Soler Sanchez T, Fernandez Garcia L, Herrero Zapatero A: Chondroid syringoma: A histological and immunohistochemical study of 15 cases. Histopathology 17: 311, 1990 https://doi.org/10.1111/j.1365-2559.1990.tb00734.x
  7. Lee JG, Oh SK, Ha JW, Choi YH, Park YE : Huge chondroid syringoma of the forehead. J Korean Soc Plast Reconstr Surg 27: 691, 2000