Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Mumps outbreak in Incheon, Korea, 2009

2009년 인천지역의 볼거리 유행 : 단일기관 연구

  • Cho, Seon Young (Departments of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Soo Young (Departments of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Kang, Jin Han (Departments of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Hwang, Hui Seung (Departments of Pediatrics, College of Medicine, The Catholic University of Korea)
  • 조선영 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이수영 (가톨릭대학교 의과대학 소아과학교실) ;
  • 강진한 (가톨릭대학교 의과대학 소아과학교실) ;
  • 황희승 (가톨릭대학교 의과대학 소아과학교실)
  • Received : 2009.06.10
  • Accepted : 2009.10.21
  • Published : 2010.01.15
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Abstract

Purpose : Recently, we have noticed an increase in the number of patients with mumps in Incheon, Korea. The aim of this study is to estimate the regional trend in mumps incidence and to evaluate the factors related to the recent increase. Methods : We reviewed the medical records of 66 patients with mumps who had been admitted to Incheon St. Mary's Hospital from July 1999 to June 2009. We compared the differences in records between "outbreak, 2009" and "nonoutbreak, 2000-2008." Results : Of the 66 patients, 35 (53%) were admitted in 2009, and 31 (47%) were admitted between 2000 and 2008. Most of the patients admitted during the outbreak were over 15 years of age (80.0%), were born before 1993 (77.1%), and had received a single dose of mumps vaccine (62.9%). There were no significant differences in contact history, present address, clinical manifestations, and complications, except for orchitis, between the two groups. Conclusion : There was a sharp increase in the number of inpatients with mumps who were born before 1993 and who were over 15 years of age. We recommend that a booster vaccination be considered for adolescents and young adults born before 1993 who are susceptible to mumps infection due to their reduced opportunities for receiving two doses of mumps vaccine.

목 적 : 최근 가톨릭대학교 인천성모병원 소아청소년과에 볼거리로 내원하는 청소년들이 증가하여, 지역 사회의 해당 질환의 역학적 변화를 대략적으로 파악하고 급증과 연관된 요인을 추정하고자 하였다. 방 법 : 1999년 7월부터 2009년 6월까지 연구병원에 볼거리로 입원한 20세 미만의 환자66명을 대상으로 인구학적 특징과 임상양상을 후향적으로 조사하였으며, 기간별로 최근 1년 급증기(2009)와 그 이외 9년 비급증기(2000-2008)로 양분하여 비교 하였다. 결 과 : 10년 동안 볼거리 입원환자 총 66명 중 35명(53%)이 최근 1년 급증기에 입원하였다. 그 이외 9년 비급증기의 입원환자수는 31명(47%)으로 연평균 $3.1{\pm}2.8$명이었다. 급증기 환자의 대부분 MMR백신을 1회 접종(62.9%)받은, 1993년 이전 출생(77.1%)한, 15-19세 연령군(80.0%)의 청소년들이었다. 볼거리 접촉력과 환자의 거주 주소지는 비급증기와 급증기에 유의한 차이가 없었으며, 급증기에 고환염과 그 연관된 증상을 보인 환자가 많다는 것 이외, 기간별로 주 증상, 합병증 및 검사실 소견에서도 임상적으로 의미 있는 차이점은 없었다. 결 론 : 최근 1년 연구병원에 볼거리 입원환자가 급증하였고 이들 대부분은, 볼거리에 자연 노출되거나 2회 MMR접종 기회가 적었던, 1993년 이전 출생한 15세 이상 청소년들이었다. 향후 광범위한 연구자료를 토대로, 볼거리 감염에 감수성이 높은 연령층에 대한 추가접종을 고려해야 할 것이다.

Keywords

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