The Transactions of The Korean Institute of Electrical Engineers (전기학회논문지)

The Korean Institute of Electrical Engineers (대한전기학회)
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Comparison of Movement of Rapid Alternating Movements of Hands in Idiopathic Parkinson's Disease Patients and Normal Subjects using Angular Velocity Measurement System

각속도 측정시스템을 이용한 특발성 파킨슨병 환자와 정상인의 빠른 손놀림 동작의 비교

  • 김지원 (건국대 의료생명대 의학공학부) ;
  • 권유리 (건국대 의료생명대 의학공학부) ;
  • 엄광문 (건국대 의료생명대 의학공학부, 건국대 의공학실용기술연구소) ;
  • 전재훈 (건국대 의료생명대 의학공학부) ;
  • 이정한 (건국대 의료생명대 의학공학부) ;
  • 이정환 (건국대 의료생명대 의학공학부) ;
  • 권도영 (고려대학교) ;
  • 고성범 (고려대학교) ;
  • 박병규 (고려대학교)
  • Published : 2010.03.01
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Abstract

The purpose of this study was to analyze bradykinesia of forearm movement in patients with Parkinson's disease (PD) as compared to those of normal subjects. A gyrosensor was selected for the measurement of forearm movement, because it can provide angular velocity signal which is free from the gravitational artifact and also because it can be conveniently used during clinical test of bradykinesia. Forty PD patients (age: $65.7\pm11.1$ yrs, H&Y stage:$2.3\pm0.5$), 14 age-matched elderly subjects ($65\pm3.9$ yrs) and 17 healthy young subjects ($24\pm2.1$ yrs) participated in this study. Angular velocity during forearm movement of pronation/supination was measured in both arms. Suggested quantitative measures of bradykinesia were root-mean-squared (RMS) angular velocity, RMS angle, peak power and total power which were derived from the angular velocity. ANOVA showed that all measures were significantly different among three groups (p<0.001). Subsequent post-hoc test revealed that all measures in PD patients were significantly smaller than in healthy elderly and healthy young subjects (p<0.05). This results suggest that PD patients can be differentiated from normal subjects using suggested measures.

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References

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