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Lifestyle and Cancer Risk

  • Weiderpass, Elisabete (Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Departmant of Etiological Research,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Departmant of Etiological Research, Cancer Registry of Norway, Department of Genetic Epidemiology, Folkhalsan Research Center, Department of Community Medicine, University of Tromso)
  • Published : 2010.11.30

Abstract

The main behavioural and environmental risk factors for cancer mortality in the world are related to diet and physical inactivity, use of addictive substances, sexual and reproductive health, exposure to air pollution and use of contaminated needles. The population attributable fraction for all cancer sites worldwide considering the joint effect of these factors is about 35% (34 % for low- and middle-income countries and 37% for high-income countries). Seventy-one percent of lung cancer deaths are caused by tobacco use (lung cancer is the leading cause of cancer death globally). The combined effects of tobacco use, low fruit and vegetable intake, urban air pollution, and indoor smoke from household use of solid fuels cause 76% of lung cancer deaths. Exposure to these behavioural and environmental factors is preventable; modifications in lifestyle could have a large impact in reducing the cancer burden worldwide. The evidence of association between lifestyle factors and cancer, as well as the main international recommendations for prevention are briefly reviewed and commented upon here.

Keywords

References

  1. World Health Organization. World Cancer Report 2002: Reducing Risk, Promoting Healthy Life. Geneva: World Health Organization; 2003.
  2. Danaei G, Vander Hoorn S, Lopez AD, Murray CJ, Ezzati M; Comparative Risk Assessment Collaborating Group (Cancers). Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors. Lancet 2005; 366(9499): 1784-1793. https://doi.org/10.1016/S0140-6736(05)67725-2
  3. Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ; Comparative Risk Assessment Collaborating Group. Selected major risk factors and global and regional burden of disease. Lancet 2002; 360(9343): 1347-1360. https://doi.org/10.1016/S0140-6736(02)11403-6
  4. Ezzati M, Lopez AD, Rodgers A, Murray CJ. Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. Geneva: World Health Organization; 2004.
  5. World Health Organization. Global Health Risks. Mortality and Burden of Disease Attributable to Selected Major Risks. Geneva: World Health Organization; 2009.
  6. World Cancer Research Fund, American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. Washington DC: AICR; 2007.
  7. Sankaranarayanan R. HPV vaccination: the promise & problems. Indian J Med Res 2009; 130(3): 322-326.
  8. Franceschi S, Cuzick J, Herrero R, Dillner J, Wheeler CM. EUROGIN 2008 roadmap on cervical cancer prevention. Int J Cancer 2009; 125(10): 2246-2255. https://doi.org/10.1002/ijc.24634
  9. Hakim AA and Dinh TA. Worldwide impact of the human papillomavirus vaccine. Curr Treat Options Oncol 2009; 10(1-2): 44-53. https://doi.org/10.1007/s11864-009-0094-4
  10. Concha-Barrientos M, Nelson DI, Driscoll T, Steenland K, Punnett L, Fingerhut MA, et al. Selected occupational risk factors. In: Ezzati M, Lopez AD, Rodgers A, Murray CJ, editors. Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors, vol 2. Geneva: World Health Organization; 2004. P. 1651-1801.
  11. Siemiatycki J, Richardson L, Straif K , Latreille B, Lakhani R, Campbell S, et al. Listing occupational carcinogens. Environ Health Perspect 2004; 112(15): 1447-1459. https://doi.org/10.1289/ehp.7047
  12. Driscoll T, Nelson DI, Steenland K , Leigh J, Concha- Barrientos M, Fingehut M, et al. The global burden of disease due to occupational carcinogens. Am J Ind Med 2005; 48(6): 419-431. https://doi.org/10.1002/ajim.20209
  13. Kim EA, Lee HE, Kang SK. Occupational burden of cancer in Korea. Saf Health Work 2010; 1(1): 61-68. https://doi.org/10.5491/SHAW.2010.1.1.61
  14. International Agency for Research on Cancer. A Review of Human Carcinogens. Radiation. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100D. Lyon: IARC; in press
  15. International Agency for Research on Cancer. Tobacco Smoke and Involuntary Smoking. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 83. Lyon: IARC; 2004.
  16. International Agency for Research on Cancer. A Review of Human Carcinogens. Lifestyle Factors. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100E. Lyon: IARC; in press
  17. Secretan B, Straif K, Baan R , Grosse Y, El Ghissassi F, Bouvard D, et al. A review of human carcinogens--Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 2009; 10(11): 1033-1034. https://doi.org/10.1016/S1470-2045(09)70326-2
  18. International Agency for Research on Cancer. Hormonal Contraception and Post-menopausal Hormonal Therapy. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 72. Lyon: IARC; 1999.
  19. International Agency for Research on Cancer. Combined Estrogen-Progestogen Contraceptives and Combined Estrogen-Progestogen Menopausal Therapy. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 91. Lyon: IARC; 2007.
  20. International Agency for Research on Cancer. A Review of Human Carcinogens. Pharmaceuticals. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100A. Lyon: IARC; in press
  21. International Agency for Research on Cancer. Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic Aromatic Amines and Mycotoxins. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 56. Lyon: IARC; 1993.
  22. International Agency for Research on Cancer. Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 82. Lyon: IARC; 2002.
  23. International Agency for Research on Cancer. A Review of Human Carcinogens. Chemical Agents and Related Occupations. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100F. Lyon: IARC; in press
  24. International Agency for Research on Cancer. Schistosomes, Liver Flukes and Helicobacter Pylori. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 61. Lyon: IARC; 1994.
  25. International Agency for Research on Cancer. A Review of Human Carcinogens. Biological Agents. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100B. Lyon: IARC; in press.
  26. International Agency for Research on Cancer. Human Immunodeficiency Viruses and Human T-Cell Lymphotropic Viruses. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 67. Lyon: IARC; 1996.
  27. World Health Organization. WHO fact sheets. Western Pacific Region. 2002 May [cited 2010 Nov 2]. Available from: http://www.wpro.who.int/media_centre/fact_sheets/fs_20020528.htm.
  28. World Health Organization. WHO framework convention on tobacco control. WHO library cataloguing-inpublication data. 2005 [cited 2010 Nov 2]. Available from: http://www.who.int/fctc/en/.
  29. World Cancer Research Fund. WCRF policy report. 2007 [cited 2010 Oct 31]. Available from: http://www.wcrfuk.org/research/cp_policy_report.php.

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