Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Secondary Metabolites of Volvariella bombycina and Their Inhibitory Effects on Melanogenesis

  • Xu, Guang-Hua (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Choo, Soo-Jin (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Young-Hee (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Ryoo, In-Ja (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Seok, Soon-Ja (Rural Development Administration (RDA), National Institute of Agricultural Science and Technology) ;
  • Ahn, Jong-Seog (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Yoo, Ick-Dong (Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2010.01.31
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Abstract

Four compounds were isolated from the culture broth of Volvariella bombycina and they were identified as ergosta-4,6,8(14),22-tetraene-3-one (1), ergosterol peroxide (2), indole-3-carboxaldehyde (3), and indazole (4) by interpretation of spectroscopic data. Among them, compound 2 exhibited melanogenesis inhibitory effect in cultured B16 mouse melanoma cells.

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References

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