The Transactions of The Korean Institute of Electrical Engineers (전기학회논문지)

The Korean Institute of Electrical Engineers (대한전기학회)
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A Study of Osteoporosis Prediction using Morphological Measuring of Proximal Femoral Part and Trabecular Characteristics Based on Femoral Radiographic Image

대퇴부 방사선영상에서 대퇴골 근위부의 형태학적 측정과 골소주의 특성을 이용한 골다공증 예측에 관한 연구

  • 김성민 (동국대_서울 의생명공학과) ;
  • 노승규 (동국대-서울 의료융합시스템연구실) ;
  • 노용만 (한국과학기술원 전자공학과)
  • Received : 2009.11.18
  • Accepted : 2010.02.17
  • Published : 2010.04.01
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Abstract

This study was designed to examine the morphological measurement and characteristics of trabecullae based on femoral radiographic image for prediction of osteoporosis. Study subjects were 34 females (average age of 62.1 years) and 6 males (average age of 60.1 years), they were categorized into normal group and osteoporosis group in accordance with the T-score value. Measurement of the bone density of femoral bone was measured with DEXA(Dual Energy X-ray absorptiometry). ROI(Region of interests) was selected on femoral neck and trochanter. Characteristics of trabecullae was analyzed by using the skeletonization analysis of trabecular image. Morphological measurement was analyzed through femoral radiographic image in order to examine the correlation with osteoporosis. The result demonstrated statistically significant correlation between neck cortical thickness, shaft width, shaft cortical thickness, periphery, mean gray level and trabeculae area with BMD average (T-score) of femoral part. The results show that morphological measurement and characteristics of trabecullae based on femoral radiographic images for osteoporosis prediction could be effective.

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References

  1. Kim K, Kushida K, Yamazaki K, Okamoto S, Inoue T, "Bone mineral density of the spine in normal Japanese subjects using dual-energy X-ray absorptiometry", effect of obesity and menopausal status. Calcif Tissue Int, vol. 49, no. 2, pp. 101-106, 1991 https://doi.org/10.1007/BF02565129
  2. Leszcynski P, Lacki JK, Mackiewicz SH, "Comparison of dual-energy X-ray absorptiometry(DXA) and quantitative ultrasonography(QUS)", Przegl Lek, vol. 60, no. 9, pp. 562-564, 2003
  3. Taguchi A, Tanimoto K, Ogawa M, Sunayashiki T, Wada T, "Effect size of size of region of interest on precision of bone mineral measurements of the mandible by quantitative computed tomography", Dentomaxillofac Radiol, vol. 20, no. 1, pp. 25-29, 1991 https://doi.org/10.1259/dmfr.20.1.1884848
  4. Hasegawa Y, Kushida K, Yamazaki K, Ionoue T, "Volumetric bone mineral density using peripheral quantitative computed tomography in Japanese women", Osteopros Int, vol. 7, no. 3, pp. 159-199, 1997 https://doi.org/10.1007/BF03194364
  5. Smith CB, Smith DA, "Relation between age, mineral density and mechanical properties of humanfemoral compacta", Acta Orthop Scand, vol. 47, no. 5, pp. 496-502, 1976 https://doi.org/10.3109/17453677608988727
  6. Consensus development conference : "Diagnosis, prophylaxis, and treatment of osteoporosis" Am J Med, vol. 1, no. 2, pp. 114-117, 1993
  7. Thomsen JS, Ebbesen En, Mosekilde L, "Relationships between static histomorphometry and bone strength measurements in human iliac crest bone bio biopsies", Bone, vol. 22, no. 2, pp. 153-163, 1998 https://doi.org/10.1016/S8756-3282(97)00235-4
  8. Geraets WG, van der Stelt PF, Netelenbos CJ, Elders PJ, "A new method for automatic recognition of the radiographic trabecular pattern", J Bone Miner, vol. 5, no. 3, pp. 227-233, 1990 https://doi.org/10.1002/jbmr.5650050305
  9. kashima I, "Computed radiography with photo-stimulable phosphor in oral and maxillpfacial radiology", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, vol. 80, no. 5, pp. 577-598, 1995 https://doi.org/10.1016/S1079-2104(05)80155-6
  10. Korstjens CM, Mosekilde L, Spruijt RJ, Geraets WG, van der Stelt PF, "Relations between radiographic trabecular pattern and biomedchanical characteristics of human vertebrae", Acta Radiol, vol. 37, no. 5, pp. 618-624, 1996 https://doi.org/10.3109/02841859609177686
  11. Shrout MK, Hildebolt CF, Potter BJ, Brunsden TK, Pilgram TK, Doston M, et al, "Comparison of morphological measurements extracted from digitized dental radiographs with lumbar and femoral bone mineral density measurements in postmenopausal women", J Periodontol, vol. 71, no. 3, pp. 335-340, 2000 https://doi.org/10.1902/jop.2000.71.3.335
  12. Shrout MK, Jett S, Mailhot JM, Potter BJ, Borke JL, Hildebolt CF, "Digital image analysis of cadaver mandibular trabecular bone patterns", J Periodontol, vol. 74, no. 9, pp. 1342-1347, 2003 https://doi.org/10.1902/jop.2003.74.9.1342
  13. Bollen Am,Taguchi A, Hujoel PP, Hollender LG, "Fractal dimension on dental radiographs", Dentomaxillofac Radiol, vol. 30, no. 5, pp. 270-275, 2001 https://doi.org/10.1038/sj.dmfr.4600630
  14. Marshall D, Johnell O, Wedel H, "Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures", BMJ, vol. 312, no. 7041, pp. 1254-1259, 1996 https://doi.org/10.1136/bmj.312.7041.1254
  15. Kanis JA, Gluer C-C, "An update on the diagnosis and assessment of osteoporosis with densitometry", Osteoporosis Int, vol. 11, no. 3, pp. 192-202, 2000 https://doi.org/10.1007/s001980050281
  16. Faulkner KG, "Bone densitometry, choosing the proper skeletal site to measure", J Clin Densitom, vol. 1, no. 3, pp. 279-285, 19981 https://doi.org/10.1385/JCD:1:3:279
  17. World Health Organization study group, "WHO Technical Report Series, Assessment of fracture risk and its application to screening for postmenopausal osteoporosis", World Health Organization, Geneva, vol. 4, no. 6, pp. 368-381, 1994
  18. White SC, Rudolph DJ, "Alterations of the trabecular pattern of the jaws in patients with osteoporosis", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, vol. 85, no. 5, pp. 625-635, 1999
  19. Young EA, "Nutrition, aging, and the aged", Med Clin North Am, vol. 67, no. 2, pp.295-313, 1983 https://doi.org/10.1016/S0025-7125(16)31205-6
  20. Ho Yeon Chung, "Osteoprrosis Diagnosis and Treatment 2007", jkes, vol. 23, pp .2-76, 2008
  21. Cummings SR, Bates D, Black DM, "Clinical use of bone densitometry", scientific review, J Am Med Assoc, vol. 288, no. 15, pp. 1889-1897, 2002 https://doi.org/10.1001/jama.288.15.1889
  22. Looker AC, Orwoll ES, Johnston CC, Jr.,Lindsay RL, Wahner HW, Dunn WL, et al, "Prevalence of low femoral bone density in older U.S", adults from NHANES III, J Bone Miner Res, vol. 12, no. 11, pp. 1761-1768, 1997 https://doi.org/10.1359/jbmr.1997.12.11.1761
  23. Kumasaka S, Kawamata R, Okada T, Miyake M, Kashima I "Relationship between bone mineral density and bone stiffness in bone fracture", Oral Radiol, vol. 21, no. 1, pp. 38-40, 2005 https://doi.org/10.1007/s11282-005-0028-1
  24. Geraets WG, van der Stelt PF, "Fractal properties of bone", Dentomaxillofac Radiol, vol. 29, no. 3, pp. 144-153, 2000 https://doi.org/10.1038/sj.dmfr.4600524
  25. Southard TE, southard KA, Jakobsen JR, Hillis SL, Najim CA, "Fractal dimension in radiographic analysis of alveolar process bone", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, vol. 82, no. 5, pp. 569-576, 1996 https://doi.org/10.1016/S1079-2104(96)80205-8
  26. Pornprasertsuk S, Ludlow JB, Webber RL, Tyndall DA, Yamauchi M, "Analysis of fractal dimensions of rat bones from film and digital images", Dentomaxillofac Radiol, vol. 30, no. 3, pp. 179-183, 2001 https://doi.org/10.1038/sj.dmfr.4600597
  27. 안병모, 허민석, 이승표, 이삼선, 최순철, 박태원 등, "노출 시간과 영상 해상도가 프랙탈 차원 값에 미치는 영향", 대한구강악안면방사선학회지, 2호, 제32권, pp. 75-79, 2002