알로에 복용 후 발생한 소아 대장 흑색증 1예

Melanosis Coli Associated with Aloe Consumption in a Child

  • 심정옥 (강원대학교 의학전문대학원 소아과학교실) ;
  • 이승구 (강원대학교 의학전문대학원 병리학교실)
  • Shim, Jeong-Ok (Department of Pediatrics, Kangwon National University School of Medicine) ;
  • Lee, Seung-Koo (Department of Pathology, Kangwon National University School of Medicine)
  • 투고 : 2010.02.03
  • 심사 : 2010.03.08
  • 발행 : 2010.03.30

초록

대장 흑색증은 장관의 점막고유층에 지방갈색소와 같은 색소를 탐식한 대식 세포의 축적에 의해 장 점막이 갈색이나 흑색으로 변하는 질환으로 anthraquinone 계통의 하제 복용과 관계있거나 노화 과정과 관계된 것으로 알려져 왔다. 대장 흑색증은 장년층 이상의 연령에서 호발하며 소아에서의 보고는 매우 드물다. 저자들은 만성 변비의 자가 치료를 위해 5개월 동안 알로에를 복용 후 6개월간 중단한 뒤에 S자결장에서 발견된 대장 흑색증을 국내 소아에서는 처음으로 보고하는 바이다.

Melanosis coli is described as a black or brown discoloration of the mucosa of the colon. Such a discoloration is largely due to pigment granule deposition in macrophages in the colonic mucosa, which arises from anthraquinone-containing laxative abuse. Melanosis coli has usually been reported in the elderly. We present the first case of melanosis coli associated with aloe consumption in a Korean child.

키워드

참고문헌

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