Pediatric Gastroenterology, Hepatology & Nutrition

  • 제13권2호
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  • Pages.172-179
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  • 2010
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  • 2234-8646(pISSN)
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  • 2234-8840(eISSN)
대한소아소화기영양학회 (The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition)
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한국 소아 청소년 남아에서 복부 지방 분포 측정의 임상적 의의

Clinical Significance of Abdominal Fat Distribution in Korean Male Children and Adolescents

  • 이연주 (울산대학교 의과대학 서울아산소아청소년병원 소아청소년과학교실) ;
  • 김경모 (울산대학교 의과대학 서울아산소아청소년병원 소아청소년과학교실) ;
  • 오석희 (울산대학교 의과대학 서울아산소아청소년병원 소아청소년과학교실) ;
  • 박혜순 (서울아산병원 가정의학과) ;
  • 명준표 (충청북도청 보건위생과 건강증진팀)
  • Lee, Yeoun-Joo (Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan Medical School) ;
  • Kim, Kyung-Mo (Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan Medical School) ;
  • Oh, Seak-Hee (Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan Medical School) ;
  • Park, Hye-Soon (Department of Family Medicine, Asan Medical Center, University of Ulsan Medical School) ;
  • Myong, Jun-Pyo (Team of Health Promotion, Division of Health and Sanitation, Chungcheongbuk-do Provincial Government)
  • 투고 : 2010.08.06
  • 심사 : 2010.09.08
  • 발행 : 2010.09.30
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초록

목 적: 성인에서 내장 지방은 대사 이상의 위험 요소와 밀접한 상관이 있다고 알려져 있으나 소아 청소년 연령에서의 연구는 미흡하다. 소아 청소년에서의 복부지방의 분포와 대사 이상의 위험 요소간에 상관성을 연구하고자 하였다. 방 법: 78명의 남아와 23명의 여아를 포함한 101명의 소아 청소년(평균 연령 10.8${\pm}$2.4세)을 대상으로 연구를 시행하였다. 신체 계측과 대사 증후군의 위험 요소에 대한 분석을 개별 환자에서 시행하였고, 복부 전산화 단층 촬영을 통해 내장 지방과 피하 지방의 양을 측정하였다. 연령을 보정한 편 상관 분석을 통해 내장 지방, 피하 지방의 양, 신체 계측 지표와 대사 이상의 위험요소 간의 상관관계를 분석하였다. 결 과: 남아와 여아 모두에서 피하 지방이 나이가 들어감에 따라서 내장 지방보다 급격히 증가하는 것을 확인할 수 있었다. 남아에서 내장 지방과 피하 지방은 신체 계측 지표와는 유의한 상관성을 보였고, 내장 지방은 낮은 수치의 HDL-C과 피하 지방은 높은 이완기 혈압과 유의한 연관성을 보였으나. 남아에서 내장 지방과 피하 지방, 신체 계측 지표는 모두 대사 이상의 위험요소의 수와 밀접한 관계가 있는 것으로 나타났다. 결 론: 남아에서 내장 지방은 낮은 수치의 HDL-C과, 피하 지방은 높은 이완기 혈압과 유의한 상관성을 나타내었으나 성인에서의 기존 연구에 비해 본 연구는 다른 대사 이상의 위험 요소들에 대한 상관성이 떨어지는 것으로 나타났다.

Purpose: Visceral adipose tissue may be strongly linked to increased metabolic risks in adults. However, because little is known regarding the effect of visceral adipose tissue in children and adolescents, we performed this study to determine the association between abdominal fat distribution and metabolic risk factors in this population. Methods: One hundred one children and adolescents (78 males and 23 females; mean age, 10.8${\pm}$2.4 years) were enrolled. The anthropometric data and metabolic risk factors were evaluated. Theabdominal fat distribution was assessed according to the CT measurement. Age-adjusted, partial correlations were performed among the visceral adipose fat area (VFA), subcutaneous adiposefat area (SFA), metabolic risk factors, and anthropometrics. Results: The SFA increased more rapidly than the VFA with advancing years in both genders. In males, the VFA and SFA were positively correlated with anthropometrics. The VFA was correlated with low HDL-cholesterol and the SFA was correlated with diastolic blood pressure (DBP). However, there was no statistical significance between the VFA, SFA, anthropometrics, and other metabolic risk factors. The VFA and SFA were strongly linked to a number of metabolic risk factors, such as other anthropometrics. Conclusion: This study investigated how a low HDL-C was correlated with VFA and how a high DBP was associated with SFA in Korean male children and adolescents. Our results suggest that the correlation between the VFA, SFA, and metabolic risk factors was relatively weak compared to that reported in previous adult studies.

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