대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

중풍 급성기에 있어서 레이저치료에 대한 최신지견 고찰 : 임상 논문을 중심으로

May Low Level Laser Therapy be the Candidate of First Choice for the Acute Stroke?

  • 양창섭 (우석대학교 한의과대학 한방내과학교실) ;
  • 장인수 (우석대학교 한의과대학 한방내과학교실) ;
  • 선승호 (상지대학교 한의과대학 한방내과학교실)
  • Yang, Chang-Sop (Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University) ;
  • Jang, In-Soo (Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University) ;
  • Sun, Seung-Ho (Dept. of Internal Medicine, College of Korean Medicine, Sang-Ji University)
  • 발행 : 2010.09.30
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초록

Background : Low level laser therapy may be an effective method to protect tissue damage in acute stroke. Recently, series of clinical studies on the basis of animal experiments report efficacy and safety of laser therapy at early stages of acute stroke. Laser promotes mitochondrial ATP synthesis to reduce cell death by ischemic infarction. Objectives : To report possibility of non-invasive laser therapy for acute stroke by reviewing literature about its effectiveness, safety and mechanism. Methods : We searched papers using PubMed and 'Web of Knowledge' of Thomson ISI, using the keywords "Laser Therapy, Low-Level" and "Stroke". Limitations were last 10 years of publications and only in English. Search range includes RCTs, clinical reports, reviews and animal experiments. Papers not matched with inclusion criteria were excluded. Results : A total 223 studies were found, 203 excluded during title and extract screening. After scanning 20 papers the final 2 serial RCTs were selected and analyzed. They reported that transcranial laser therapy led in neuroprotective effect for acute stroke patents. Clinical evaluation factors showed favorable trend and initial safety. Conclusions : Non-invasive laser secured safety of clinical application. It may be a favorable choice for the acute stage of stroke.

키워드

참고문헌

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