Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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A Study on the Effect of Herbal-acupuncture with Artemisiae Capillaris Herba at GB34 on Hyperlipidemia in Rat

양릉천 인진 약침이 흰쥐의 고지혈증에 미치는 영향

  • Lee, Jung-Tae (Dept. of Meridian & Acupoint, College of Oriental Medicine, Daejeon University) ;
  • Lee, Byung-Ryul (Division of Clinical Medicine, School of Korean Medicine, Pusan National University) ;
  • Yang, Gi-Young (Division of Clinical Medicine, School of Korean Medicine, Pusan National University) ;
  • Lee, Hyun (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Yim, Yun-Kyoung (Dept. of Meridian & Acupoint, College of Oriental Medicine, Daejeon University)
  • 이정태 (대전대학교 한의과대학 경락경혈학교실) ;
  • 이병렬 (부산대학교 한의학전문대학원 임상의학부) ;
  • 양기영 (부산대학교 한의학전문대학원 임상의학부) ;
  • 이현 (대전대학교 한의과대학 침구학교실) ;
  • 임윤경 (대전대학교 한의과대학 경락경혈학교실)
  • Received : 2010.03.04
  • Accepted : 2010.03.23
  • Published : 2010.03.27
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Abstract

Objective & Methods: The purpose of this study is to investigate the effects of Artemisiae Capillaris Herba herbal-acupuncture (ACH-HA) at GB34 (Yangleungchean) on hyperlipidemia induced with alloxan injection and high fat diet in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta. Results: 1. ACH-HA solution increased the DPPH radical scavenging activity in rat liver cells. 2. ACH-HA at GB34 significantly decreased the levels of serum total cholesterol, low-density lipoprotein (LDL)-cholesterol, free cholesterol and atherogenic index (AI), while significantly increased the ratios of high-density lipoprotein (HDL)/total cholesterol and phospholipid/total cholesterol in hyperlipidemic rats. 3. ACH-HA at GB34 significantly decreased serum aspartate aminotransferase (AST) level in hyperlipidemic rats. 4. ACH-HA at GB34 significantly increased hepatic glutathione (GSH) activity in hyperlipidemic rats. Conclusion: From the above results, it is suggested that ACH-HA at GB34 may have therapeutic and preventive effects on hyperlipidemia.

Keywords

References

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