Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

Comparative studies of effects of manual acupuncture, invasive laser acupuncture and laser skin irradiation at the Heart Jeonggyeok acupoint on the focal ischemia induced by intraluminal filament insertion in rats

심정격(心正格) 혈위(穴位)에 시술한 침자(鍼刺)와 침습(侵襲)및 비침습(非侵襲) 레이저침요법(鍼療法)이 뇌허혈(腦虛血)에 미치는 영향(影響)에 대한 비교(比較) 연구(硏究)

  • Youn, Jeong-Young (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Kim, Young-Sun (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Youn, Dae-Hwan (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Lee, Suk-Hee (Dept. of Mechatronics, Gwangju Institute of Science Technology) ;
  • Oh, Gwang-Hwan (Korea Institute of Industrial Technology) ;
  • Jeong, Sung-Ho (Dept. of Mechatronics, Gwangju Institute of Science Technology) ;
  • Na, Chang-Su (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University)
  • 윤정영 (동신대학교 한의과대학 경락경혈학교실) ;
  • 김영선 (동신대학교 한의과대학 경락경혈학교실) ;
  • 윤대환 (동신대학교 한의과대학 경락경혈학교실) ;
  • 이석희 (광주과학기술원 기전공학과) ;
  • 오광환 (한국생산기술연구원) ;
  • 정성호 (광주과학기술원 기전공학과) ;
  • 나창수 (동신대학교 한의과대학 경락경혈학교실)
  • Received : 2010.03.04
  • Accepted : 2010.03.23
  • Published : 2010.03.27
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Abstract

Objectives: The purpose of this study was to identify the effectiveness of neuronal activities for the acupuncture and laser acupuncture application. Methods: The subject were divided into 7 groups as control group without acupuncture, acupuncture treatment with tonify manipulation with the direction of channel at HT9, LR1(AT-A), acupuncture treatment with purge manipulation against the direction of channel at HT3, Kl10(AT-B), acupuncture treatment with tonify manipulation with the direction of channel at HT9, LR1 and purge manipulation against the direction of channel at HT3, KI10(AT-C), laser acupuncture treatment with red light 658 nm at HT9, LR1(LAT-A), laser acupuncture treatment with green light 532 nm at HT3, KI10(LAT-B), laser acupuncture treatment with red light 658 nm at HT9, LR1 and green light 532 nm at HT3, KI10(LAT-B). Antiapopotic effect of acupuncture was observed by Bax, Bcl-2 and cytochrome C. Neuroprotective effect of acupuncture was observed by cresyl violet and ChAT. Results: AT-A, AT-B, AT-C, LAT-A, LAT-B and LAT-C groups were significantly increased comparing the control groups in expression ChAT and in neuroprotective effect by cresyl violet. AT-A, AT-B, AT-C, LAT-A, LAT-B and LAT-C groups were significantly decreased comparing the control groups in expression Bax. AT-C, LAT-A, LAT-B and LAT-C groups were significantly increased comparing the control groups in expression Bcl-2. AT-A, AT-B, AT-C, LAT-A, LAT-B and LAT-C groups were significantly decreased comparing the control groups in Bax/Bcl-2 ratio. LAT-B and LAT-C groups were significantly decreased comparing the control groups in expression cytochrome C. Conclusions: The acupuncture with tonify and purge manipulation and laser acupuncture with red and green light could be effective for antiapopotic and neuroprotective effect in focal brain ischemia.

Keywords

References

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