Preparation and Characterization of Gelatin Scaffold Containing Microorganism Fermented Cellulose

미생물 발효 셀룰로오스와 젤라틴을 함유한 조직공학적 세포지지체의 제조 및 특성

  • Lim, Youn-Mook (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Kim, Mi-Yeong (Quegenbiotech, Co., Ltd) ;
  • Gwon, Hui-Jeong (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Park, Jong-Seok (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Nho, Young-Chang (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Lee, Byeon-Heon (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Lee, Jong-Dae (Quegenbiotech, Co., Ltd) ;
  • Song, Sung-Gi (Quegenbiotech, Co., Ltd) ;
  • Kim, Sung-Ho (Department of Bio-Food, Kyungpook National University) ;
  • Choi, Young-Hun (Citrus Research Station, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Lee, Sun-Yi (Citrus Research Station, National Institute of Horticultural and Herbal Science, Rural Development Administration)
  • 임윤묵 (한국원자력연구원 정읍방사선과학연구소) ;
  • 김미영 ((주)큐젠바이오텍) ;
  • 권희정 (한국원자력연구원 정읍방사선과학연구소) ;
  • 박종석 (한국원자력연구원 정읍방사선과학연구소) ;
  • 노영창 (한국원자력연구원 정읍방사선과학연구소) ;
  • 이병헌 (한국원자력연구원 정읍방사선과학연구소) ;
  • 이종대 ((주)큐젠바이오텍) ;
  • 송성기 ((주)큐젠바이오텍) ;
  • 김성호 (경북대학교 바이오 식품과) ;
  • 최영훈 (농촌진흥청 국립원예특작과학원 감귤시험장) ;
  • 이선이 (농촌진흥청 국립원예특작과학원 감귤시험장)
  • Received : 2010.11.26
  • Accepted : 2010.11.30
  • Published : 2010.12.30

Abstract

Cellulose, chitin, chitosan and hyaluronic acid are well known as polysaccharides. These polysaccharides have many effects on cell growth and differentiation. Cell activation increases with increasing the polysaccharides concentration. In this study, gelatin scaffold containing microorganism fermented cellulose, citrus gel were prepared by using irradiation technique. Physical properties of the scaffolds were investigated as a function of the concentrations of gelatin and citrus gel and the cell attachment, cell morphology and inflammation of the scaffolds also were characterized for regeneration of skin tissue.

Keywords

Acknowledgement

Supported by : 농촌진흥청