The Journal of Korea Assosiation for Disability and Oral Health (대한장애인치과학회지)

Korean Association for Disability and Oral Health (대한장애인치과학회)
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Disturbances of maxillofacial and dental development after cancer therapy: Case reports

항암치료 후 악골 및 치아의 발육 장애: 증례보고

  • Kim, Hyo-Jung (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
  • Kim, Chong-Chul (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
  • 김효정 (서울대학교 대학원 치의학과 소아치과학교실) ;
  • 김종철 (서울대학교 대학원 치의학과 소아치과학교실)
  • Received : 2010.12.10
  • Accepted : 2010.12.22
  • Published : 2010.12.31
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Abstract

Chemotherapy and radiotherapy proved conservative and effective in treating tumors. However, both the cancer therapies will also have aberrant effects on developing maxillofacial and dental organs of children. The purpose of this report is to describe the clinical cases of Disturbances of maxillofacial and dental development after Cancer therapy. The first case reported a 7-year-old female patient diagnosed at age 2 years with bilateral retinoblastoma, receiving chemotherapy and radiotherapy. She had agenesis of premolar, microdontia, short tapered teeth in lower anterior area and generalized root stunting. The second case presented a 12-year-old female patient treated with chemotherapy and radiotherapy for neuroblastoma in her early childhood. She presented with a class III malocclusion on a skeletal III base due to maxillary retrognathism. Contemporay oncology had improved survival of children with malignant disease. It will be needed prevention of these side effect after cancer therapy to improve the quality of life.

화학치료와 방사선 치료는 보존적이고 효과적인 항암치료 방법이다. 그러나 악골 및 치아의 성장이 완료되지 않은 성장기 아동의 경우에는 발육 장애를 유발할 수 있다. 환자 의 삶의 질 개선을 위해 이러한 부작용을 예방할 수 있는 방법이 모색되어야 할 것이다.

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