Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

Anti-wrinkle Effects of Cervi Pantotrichum Cornu Pharmacopuncture Solution

녹용 약침액의 주름 개선 효과에 관한 연구

  • Lee, Ju-Hee (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daegu Hanny University) ;
  • Lee, Kyung-Min (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daegu Hanny University) ;
  • Kim, Jae-Su (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daegu Hanny University) ;
  • Jung, Tae-Young (Je-Han Oriental Medical Academy) ;
  • Lim, Seong-Chul (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daegu Hanny University)
  • 이주희 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 이경민 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 김재수 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 정태영 (제한동의학술원) ;
  • 임성철 (대구한의대학교 한의과대학 침구경혈학교실)
  • Received : 2010.05.22
  • Accepted : 2010.07.26
  • Published : 2010.08.20
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Abstract

목적 : 본 연구는 녹용약침액의 주름 개선 효과에 대하여 여러 가지 in vitro 실험을 통해 확인해 보고자 계획되었다. 방법 : 녹용약침액의 항산화효과를 DPPH(1,1-diphenyl-2-picrylhydrazyl) 자유라디칼 소거법을 이용하여 측정하였고, 또, elastase 억제 효과를 측정하였다. 그리고 녹용약침액이 사람 정상 섬유아세포 HS 68에서 UVB 조사 후 type I procollagen의 생산량 회복에 미치는 효과를 ELISA법을 이용하여 측정하였다. 결과 : 녹용약침액에서 우수한 DPPH 자유라디칼 소거 효과가 관찰되었다. 또한 통계적으로 유의한 elastase 활성 억제 효과를 관찰할 수 있었다. 사람 섬유아세포 HS 68을 이용한 실험에서는 녹용약침액 처치군에서 UVB 조사로 감소된 type I procollagen이 유의하게 회복되는 것이 관찰되었다. 결론 : 본 연구 결과에 의하면, 녹용약침액에는 유효한 주름개선 효과가 있어, 미용약침 소재로 개발할 수 있을 것으로 사료된다.

Keywords

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