DOI QR코드

DOI QR Code

GARRE'S OSTEOMYELITIS IN CHILDREN

소아에서의 Garre 골수염

  • Woo, Se-Eun (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Kim, Young-Jin (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Kim, Hyun-Jung (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Nam, Soon-Hyeun (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University)
  • 우세은 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 김영진 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 김현정 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 남순현 (경북대학교 치의학전문대학원 소아치과학교실)
  • Received : 2011.03.31
  • Accepted : 2011.11.05
  • Published : 2011.11.30

Abstract

Garre's osteomyelitis is associated with bacterial infection and bone necrosis resulting from obstruction of blood supply. The most common cause for Garre's osteomyelitis is odontogenic infection that originates from periodontal tissue or dental pulp. Subperiosteal abscess may also cause Garre's osteomyelitis in the progress of the infection. Mandible is more often affected than maxilla, most commonly in the permanent first molar region of mandible. Clinically, it results in a hard swelling over the jaw, producing facial asymmetry. Meanwhile, radiograph shows a characteristic feature of irregular pulpal cavity, showing new periosteal proliferation located in successive layers to the condensed cortical bone on stimulated site. The treatment method for Garre's osteomyelitis are removal of the infection source, root canal treatment, antibiotic medication, and incision and drainage. This report presents a case of Garre's osteomyelitis under 15 years old. The patient was successfully treated by antibiotic medication accompanied with root canal treatment. Since the symptom of pediatric patients is less severe than adult, careful diagnosis with history taking and clinical examination is necessary. Furthermore long-term follow-up examination is needed to prevent recurrence even after the symptom disapears.

Garre 골수염은 혈류 순환 및 영양 공급의 장애로 골이 괴사되거나, 세균 감염이 증가되면 발생한다. Garre 골수염은 치수나 치주 감염에서 시작된 치성계 감염과 이의 진행에 따른 골막 하 농양이 주요 원인이 되며, 외상으로 인한 악골의 복합 골절시 2차 감염, 국소적인 치은의 외상에 의해서도 발생할 수 있다. 상악에서보다 하악에서 많이 발생되며 호발 부위는 하악 제1대구치이다. 임상증상으로 이환 부위의 하악골은 팽창되어 있으나 구강점막은 정상적 색조를 가지며 안면 불균형을 나타낸다. 방사선사진 상 심한 우식증을 가진 치아의 치근단 병소를 관찰할 수 있으며, 자극을 받는 골조직 부위의 치밀골 증가로 골수강은 좁아지거나 폐쇄되며 외양이 불규칙하게 나타난다. 치료 방법으로는 항생제의 투여, 원인치의 발치 또는 근관치료, 절개 및 배농술 등이 알려져 있다. 본 증례는 15세 이하의 소아환자에서 악골 골수염이 발생한 경우, 장기적인 항생제 투여나 항생제 투여 및 근관 치료를 병용하여 성공적으로 치료된 증례이다. 소아 환자의 경우 성인에 비하여 증상이 경미하므로 주의 깊은 병력 청취와 임상 검사를 통한 진단이 요구되며, 증상이 사라진 경우에도 재발을 방지하기 위하여 장기간의 추적 검사가 요구된다.

Keywords

References

  1. Garre C : Ueber benzondere foraman and folgezustande der akutn infektiosen, osteomyelitis. Beitrklin Chil, 10:241-298, 1893.
  2. Berger A : Perimandibular ossification of possible traumatic origin. : report case. J Oral Surg, 6:353-356, 1948.
  3. Pell GJ, Shafer WC, Gregory GT, et al. : Garre's osteomyelitis of the mandible: report of case. J Oral Surg, 13:548-252, 1955.
  4. Eversole LR, Leider AS, Corwin JO, et al. : Proliferative periostitis of Garre's : Its Differentiation from other neoperiostoses. J Oral Surg, 37:725-731, 1979.
  5. Lichty G, Langlaris RP, Aufdemorta T : Garre's osteomyelitis : literature review and case report. J Oral Surg, 50:309-313, 1980. https://doi.org/10.1016/0030-4220(80)90412-0
  6. Batcheldor Jr GD, Giansanti JS, Hibbard ED, et al. : Garre's osteomyelitis of the jaws : a review and report of two cases. JADA, 87:892-897, 1973.
  7. Schwartz S, Pham H : Garre's osteomyelitis : A case report. Pediatric Dentistry, 283-286, 1981.
  8. Smith SN, Forman AG : Osteomyelitis with Proliferative Periostitis(Garre's Osteomyelitis) : Report of Case Affecting the Mandible, J Oral Surg, 43:315-318, 1997.
  9. Pauder AK, Hadders HNI : Chronic sclerosing inflammations of the jaw: Osteomyelitis sica (Garre) chronic sclerosing osteomyelitis with fine-meshed trabecular structure, and very dens sclerosing osteomyelitis. J Oral Surg, 30:392-412, 1970.
  10. Ritvo Max : Bone and Joint X-ray Diagnosis. J Bone & Joint Surg , 38:954-955, 1956.
  11. Farole A, Aldesic EC : Garre's Osteomyelitis : Report case associated with a granuloma, J. of Dentistry for Children, 214-217, 1966.
  12. McWalter GM, Schaberg SJ : Garre's osteomyelitis of the mandible resolved by Endodontic Treatment. JADA, 108:193-195, 1984.
  13. Ellis DJ, Winslow JR, Indovina AA : Garre's osteomyelitis of the mandible. J Oral Surg, 44:183-189, 1977. https://doi.org/10.1016/0030-4220(77)90266-3
  14. Thoma KH : Garre's osteomyelitis of the Mandible. J Oral Surg, 9:444-449, 1956. https://doi.org/10.1016/0030-4220(56)90034-2
  15. Monteone L, Tampa Fla : Garre's osteomyelitis. J. of Surg, 50:423-431, 1962.
  16. Sanders B : Garre's sclerosing Osteomyelitis, Textbook of Pediatric Oral Maxillofacial Surgery. C.V. Mosby Company: St Louis, 385-393, 1979.
  17. Gentry LO : Osteomyelitis: options for diagnosis and management. J Antimicrob Chemother, 21:115-131, 1988. https://doi.org/10.1093/jac/21.suppl_C.115
  18. Seward GR : The correlation of radiographical and clinical information. D. Practitioner, 6:212-215, 1956.
  19. Loveman CE : Mandibular Subperiosteal Swelling in Children, JADA, 28:1230, 1941.
  20. Bhaskar SN : Synopsis of oral pathology. C.V. Mosby Company: St Louis, 334-335, 1977.
  21. Petrikowski CG, Pharoah MJ, Lee L, et al. : Radiographic differentiation of osteogenic sarcoma, osteomyelitis, and fibrous dysplasia of the jaws. Oral Surg Oral Med Oral Pathol Oral Radial Endod, 80:744-750, 1995. https://doi.org/10.1016/S1079-2104(05)80260-4
  22. Boyne PJ : Physiology of bone and response of osseous tissue to injury and environmental changes. J Oral Surg, 28:12-15, 1970.
  23. Mainous EG, Boyne PJ, Hart GB : Elimination of sequestrum and healing of osteoradionecrosis of the mandible after hyperbaric oxygen therapy. J Oral Surg, 31:335-336, 1973.
  24. Mansfield MJ, Saunders DW, Heimbach RD, et al. : Hyperbaric oxygen an adjunct in the mandible. J Oral Surg, 39:585-588, 1981.
  25. Marx RE : Hyperbaric oxygen therapy in bony reconstruction of the irradiated and tissue deficient patient. J Oral Maxillofac Surg, 40: 412-414, 1982. https://doi.org/10.1016/0278-2391(82)90076-3
  26. Hjorting-Hansen E : Decortication in treatment of osteomyelitis of the mandible. Oral Surg Oral Med Oral Pathol, 29:641-655, 1970. https://doi.org/10.1016/0030-4220(70)90259-8
  27. Kruger E and Worthington P : Oral Surgery in Dental practice. Quintessence: Chicago, 1981. Cited by 김여갑 : 임상구강악안면감염학. 의치학사, 215-252, 1995.