Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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Simultaneous Spectral Resolution and Sensitivity Enhancement in MR spectrum: Maximum Likelihood Deconvolution Reconstruction

  • Jeong, Gwang-Woo (Department of Radiology, Chonnam National University Hospital, Chonnam National University Medical School) ;
  • Jeong, Jenny Eunice (Department of Electronics Engineering, Ewha Womans University) ;
  • Kang, Heoung-Keun (Department of Radiology, Chonnam National University Hospital, Chonnam National University Medical School)
  • Received : 2011.11.30
  • Accepted : 2011.12.13
  • Published : 2011.12.20
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Abstract

Although the use of apodization functions in connection with postprocessing of a 2D NMR spectrum proves improved spectral quality, there is usually a trade-off between resolution enhancement and noise suppression due to a classical "uncertainty principle." In this study, therefore, a mathematical deconvolution technique called "Maximum Likelihood Deconvolution (MLD)" was adopted to achieve the spectral resolution and sensitivity enhancement simultaneously. The MLD technique greatly facilitates visualization and restoration of the genuine spectral information from complex 2D NMR spectra that would be problematic with the conventional apodization/FT processing. In particular, application of the MLD to the 2D-NOE spectrum would be very useful to derive the important proton connectivities, which are essential to achieve elucidating the 3D molecular structure.

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