Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Changes in Distribution of Electrical Field in tDCS with Ring Electrode Due to Tissue Anisotropy: a 3D High Resolution Finite Element Head Model Study

경두개직류자극 전기장의 분포 특성에 비등방성 전기 전도율이 미치는 영향 분석 :3차원 고해상도 유한요소 두뇌 모델을 통한 연구

  • Kim, Sang-Hyuk (Department of Biomedical Engineering, Kyung Hee University) ;
  • Suh, Hyun-Sang (Department of Biomedical Engineering, Kyung Hee University) ;
  • Cho, Young-Sun (Department of Biomedical Engineering, Kyung Hee University) ;
  • Lee, Won-Hee (Department of Biomedical Engineering, Columbia University) ;
  • Kim, Tae-Seong (Department of Biomedical Engineering, Kyung Hee University)
  • 김상혁 (경희대학교 생체의공학과) ;
  • 서현상 (경희대학교 생체의공학과) ;
  • 조영선 (경희대학교 생체의공학과) ;
  • 이원희 (컬럼비아대학교 의공학과) ;
  • 김태성 (경희대학교 생체의공학과)
  • Received : 2011.07.06
  • Accepted : 2011.08.25
  • Published : 2011.12.30
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Abstract

For effective stimulation with tDCS, spatial focality of induced electrical field(EF) and current density(CD) is one of the important factors to be considered. Recently, there have been some studies to improve the spatial focality via different types of electrodes and their new configurations: some improvements using ring electrodes were reported over the conventional pad electrodes. However, most of these studies assumed isotropic conductivities in the head. In this work, we have investigated the effect of tissue anisotropy on the spatial focality of tDCS with the 4 + 1 ring electrode configuration via a 3-D high-resolution finite element(FE) head model with anisotropic conductivities in the skull and white matter. By examining the profiles of the induced EF from the head models with isotropic and anisotropic conductivities respectively, we found that the spatial focality of the induced EF significantly drops and get diffused due to tissue anisotropy. Our analysis suggests that it is critical to incorporate tissue anisotropy in the effective stimulation of the brain via tDCS.

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References

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