감각과 운동 신경의 재생을 동반한 중안모 동종이식 모델

Composite Midface Allotransplantation Model with Sensory and Motor Reinnervation

  • 유명수 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소) ;
  • 김성민 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소) ;
  • 서미현 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소) ;
  • 명훈 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소) ;
  • 이종호 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소) ;
  • 최진영 (서울대학교 치의학대학원 구강악안면외과학교실, 치학연구소)
  • Yu, Myung-Soo (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University) ;
  • Kim, Soung-Min (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University) ;
  • Seo, Mi-Hyun (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University) ;
  • Myoung, Hoon (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University) ;
  • Lee, Jong-Ho (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University) ;
  • Choi, Jin-Young (Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry Seoul National University)
  • 발행 : 2011.12.30

초록

Face transplantation has been reported over the last six years, and it started in 2004 with the announcement of Cleveland Clinic granting the world's first IRB approval to proceed with human face transplantation. Composite tissue allografts (CTAs) in the facial region are considered to be more immunogenic than other solid organ transplants, so these kinds of animal experiments were also considered as challengeable activities to the facial reconstructive surgeons. For the better understanding of CTAs in the oral and maxillofacial fields, we reviewed several recent articles about facial composite transplantation animal model, and summarized some knowledges of composite midface allotransplantation model with sensory and motor reinnervation in this review article.

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