Food Science and Preservation (한국식품저장유통학회지)

The Korean Society of Food Preservation (한국식품저장유통학회)
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Comparison of Anti-Adipogenesis Activity by Several Grape Extracts

포도 추출물로부터 C/EBP 전사인자 활성 비교

  • Lee, Si-Rim (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Park, Chul-Hong (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Kuan, Eun-Young (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Lu, Yan-Qing (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Hong (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Ki-Chan (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Son, Hyeong-U (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Lee, Hyun-Jin (Department of Food Science and Biotechnology, Kyungpook National University) ;
  • Heo, Jin-Chul (Food and Bio-Industry Research Institute, Kyungpook National University) ;
  • Lee, Sang-Han (Department of Food Science and Biotechnology, Kyungpook National University)
  • 이시림 (경북대학교 농업생명과학대학 식품공학과) ;
  • 박철홍 (경북대학교 농업생명과학대학 식품공학과) ;
  • 권은영 (경북대학교 농업생명과학대학 식품공학과) ;
  • 루옌칭 (경북대학교 농업생명과학대학 식품공학과) ;
  • 김홍 (경북대학교 농업생명과학대학 식품공학과) ;
  • 김기찬 (경북대학교 농업생명과학대학 식품공학과) ;
  • 손형우 (경북대학교 농업생명과학대학 식품공학과) ;
  • 이현진 (경북대학교 농업생명과학대학 식품공학과) ;
  • 허진철 (경북대학교 식품생물산업연구소) ;
  • 이상한 (경북대학교 농업생명과학대학 식품공학과)
  • Received : 2010.09.28
  • Accepted : 2011.01.28
  • Published : 2011.02.28
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Abstract

In order to compare what kinds of transcription factors are associated with the inhibition of preadipocyte cell proliferation, we prepared several grape extracts and tested the expression patterns by reverse transcription-polymerase chain reaction. As a result, 50% ethanol extract of Campbell early seed inhibited adipogenesis derived from the MDI solution. Extract of Campbell early seed was significantly inhibited lipid droplet formation and expression of molecular factors C/EBP-alpha and delta in 3T3-L1 cells. It is suggested that grape extracts of fractions would be a good candidate for the development of regional skin fat modulator.

Keywords

References

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