개에서 복강경을 이용한 난소자궁절제술시 $CO_2$가스에 의한 기복증이 심박수와 동맥혈압에 미치는 영향

Effects of Using Carbon Dioxide on Heart Rate and Arterial Blood Pressure during Laparoscopic Ovariohysterectomy in Dogs

  • 조성수 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 김영기 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 박세진 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 이승용 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 이시경 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 이희천 (경상대학교 수의과대학 동물의학연구소) ;
  • 이효종 (경상대학교 수의과대학 수의외과, 행동학 연구실) ;
  • 장홍희 (경상대학교 수의과대학 동물의학연구소) ;
  • 연성찬 (경상대학교 수의과대학 수의외과, 행동학 연구실)
  • Cho, Seong-Su (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Kim, Young-Ki (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Park, Se-Jin (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Seung-Yong (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Scott-S. (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hyo-Jong (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University) ;
  • Chang, Hong-Hee (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Yeon, Seong-Chan (Lab. of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University)
  • 심사 : 2010.10.04
  • 발행 : 2011.02.28

초록

Cardiovascular changes caused by $CO_2$ pneumoperitoneum during laparoscopic ovariohysterectomy (LOVH) were measured in nine healthy mixed breed dogs ($16.7{\pm}4.6kg$). The dogs were premedicated with the combination of atropine, acepromazine, and butorphanol. General anesthesia was induced with propofol and maintained with isoflurane in oxygen. Controlled ventilation maintained partial pressure of end-tidal $CO_2$ between 35-45 mmHg. The $CO_2$ pneumoperitoneum was maintained at a constant pressure of 12 mmHg and the dog was placed in the $15^{\circ}$ Trendelenburg position as LOVH was performed. Dorsal pedal artery was catheterized for measurements of heart rate (HR) and invasive arterial blood pressure (IBP). Prior to the intraperitoneal insufflation, baseline measurements of HR and IBP were made every minute for a total of 10 min. Then, measurements of HR and IBP were made every 5 min following intraperitoneal insufflation and were also made every 5 min following desufflation for a total of 10 min. The $CO_2$ pneumoperitoneum during LOVH resulted in a significant (P < 0.05) increase in systolic arterial blood pressure at the time of the onset of insufflation. In addition, diastolic and mean arterial blood pressure increased significantly (P < 0.05) at the time of the onset of insufflation and 5 min following insufflation. The mean heart rate did not change significantly during LOVH. Although IBP showed sharp initial rise following the $CO_2$ pneumoperitoneum, the changes were within physiological acceptable limits in these healthy, ventilated dogs.

키워드

참고문헌

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