Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
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Preparation and Characteristics of Bioactive Silica-free Calcium Phosphate Glass-ceramics

실리카를 함유하지 않는 생체활성 칼슘인산염 글라스-세라믹스의 합성 및 특성

  • Song, Chang-Weon (School of Materials Science and Engineering, Pusan National University) ;
  • Lee, Joo-Hyeok (School of Materials Science and Engineering, Pusan National University) ;
  • Yang, Tae-Young (School of Materials Science and Engineering, Pusan National University) ;
  • Yoon, Seog-Young (School of Materials Science and Engineering, Pusan National University) ;
  • Park, Hong-Chae (School of Materials Science and Engineering, Pusan National University)
  • Received : 2011.03.31
  • Accepted : 2011.04.07
  • Published : 2011.05.31
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Abstract

Glass-ceramic materials, which consist of glass matrix phase containing crystalline ${\beta}-Ca_3(PO_4)_2$ and ${\beta}-Ca_2P_2O_7$, have been prepared by heating at $750-900^{\circ}C$ of calcium phosphate invert glasses in the silica-free $CaO-P_2O_5-TiO_2-Na_2O$, system. With increasing heating temperature from 750 to $900^{\circ}C$, the crystallite size of precipitated ${\beta}-Ca_3(PO_4)_2$ in glass with $55CaO{\cdot}35P_2O_5{\cdot}3TiO_2{\cdot}7Na_2O$ (mol%) composition increased from 48 to 91 nm. With the extension of the immersion time in dilute acetic acid solution (pH = 5) to ${\geq}$200 min, the degree of dissolution of $Ca^{2+}$ and $P^{5+}$ ions in the glass-ceramics was linearly increased and the solution was constantly maintained at pH = ~7. Biomimetic nanostructured (62-88 nm in average dia.), sphere-shaped hydroxyapatite was homogeneously formed on the surface of the glass-ceramics when socked for 7-14 days in a Hanks' solution, indicating bioactivity of the prepared glass-ceramics.

Keywords

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