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The Anti-Wrinkle and Whitening Effect of Extracts of Castanea crenata Inner Shell

밤부산물(율피)의 주름개선 및 미백 효과

  • 장민정 ((주)아쎄엠코리아 연구소) ;
  • 천순주 (대구한의대학교 화장품약리학과) ;
  • 김희영 (대구한의대학교 화장품약리학과) ;
  • 권대준 (대구테크노파크 바이오헬스융합센터) ;
  • 김학윤 (계명대학교 환경생물학) ;
  • 김세현 (국립산림과학원 산림자원육성부) ;
  • 이진태 (대구한의대학교 화장품약리학과)
  • Received : 2011.02.17
  • Accepted : 2011.05.25
  • Published : 2011.05.30

Abstract

Aging in humans is inexorable and inescapable. The progressive decrease of physiological capacity and the reduction of the ability to cope with environmental stresses lead to increased susceptibility and vulnerability to human disease. Recently, in the cosmetic industry, many researchers have paid considerable attention to delaying or improving the symptoms of skin aging. Since the early 1990`s, there have been various challenges in developing cosmeceutical products which have strong anti-aging effects, and this has been an important issue in the cosmetic industry. Meanwhile, development of anti-aging cosmetics supported by biochemical activities in the skin has been researched. Castanea crenata inner Shell solvent extracts were investigated for anti-wrinkle and whitening effects, in order to apply it as a functional ingredient for cosmetic products. For anti-wrinkle effect, elastase inhibition activity of Castanea crenata inner shell acetone extract (CA) was 51.0% at a concentration of 100 ug/ml. The collagenase inhibition activity of CA and Castanea crenata inner shell ethanol extract (CE) was 96.4%, 94.3% at a concentration of 50 ug/ml. The tyrosinase inhibitory effect, which is related to skin-whitening, was 47.2% and 45.8% in CA and CE at a concentration of 500 ug/ml. All these results suggest that Castanea crenata inner shell can be effectively used as a cosmeceutical ingredient for the prevention of wrinkles.

율피를 기능성 화장품 소재로 활용하기 위하여 주름개선, 미백 및 수렴효과를 검증하였다. 주름개선 효과를 검증하기 위하여 elastase 저해활성과 collagenase 저해활성을 측정하였다. Elastase 저해활성을 측정한 결과 율피 아세톤 추출물 100 ug/ml에서 51.0%의 효과를 나타내었으며, collagenase 저해활성을 측정한 결과 아세톤 및 에탄올 추출물이 50 ug/ml 에서 96.4%, 94.3%의 저해활성을 나타내었다. 미백효과를 확인하기 위하여 tyrosinase 저해활성을 측정한 결과 아세톤 및 에탄올 추출물이 열수 추출물보다 높은 Tyrosinase 저해활성을 나타내었으나 대조군으로 사용한 Vitamin C와 비교시 약 50%의 효과를 나타내었다. 이상의 결과로 미루어 보아 율피 추출물의 주름개선 효과가 높음을 확인할 수 있었고, 주름개선 기능성 화장품 소재로서의 가능성을 확인하였다.

Keywords

References

  1. Cannell, R. J., S. J. Kellam, A. M. Owsianks, and J. M. Malker. 1988. Results of a large scale screen of microalgae for the production of protease inhibitors. Planta Med. 54, 10-14. https://doi.org/10.1055/s-2006-962319
  2. Gomes, A., J. R. Vedasiromoni, M. Das, R. M. Sharma, and D. K. Ganguly. 1995. Anti-hyperglycemic effect of black tea (Camelliasinensis) inrat. J. Ethnopharmacol. 45, 223-226. https://doi.org/10.1016/0378-8741(95)01223-Z
  3. Imokawa, G. and Y. Mishima. 1981. Biochemical characterization of tyrosinase inhibitors using tyrosinase binding affinity chromatography. Br. J. Dermatol. 104. 513-539.
  4. Kang, K. S. 2007. The Evalution of Anti-wrinkle Effects in Oriental herb extract. J. Life Sci. 17, 1147-1151. https://doi.org/10.5352/JLS.2007.17.8.1147
  5. Kim, S. N., S. H. Lee, B. K. Lee, and I. S. Jang. 2002. A compositions containing Anthriscus sylvestris Hoffmann extract or Petroselinum sativum Miller extract for external application having effects of improving skin wrinkle. Korea Institute of Patent Information. 10-2002-0079594
  6. Kim, Y. G., Y. H. Lee, M. K. Kang, B. H. Lee, J. K. Yun, S. B. Kim, and C. J. Kim. 2009. Preparation of functional cosmetics containing $\beta$-carotene derived from recombinant Escherichia coil and evaluation of anti-wrinkle efficacy by clinical testing. Korean J. Microbiol. Biotechnol. 37, 399-404.
  7. Kligman, D. 2000. Cosmeveuticals. Dermatol. Clin. 18, 609-615. https://doi.org/10.1016/S0733-8635(05)70211-4
  8. Kwak, Y. J., D. H. Lee, N. M. Kim, and J. S. Lee. 2005. Screeing and extraction condition of anti-skin aging elastase inhibitor from medicinal plants. Korean J. Medicinal Crop Sci. 13, 213-216.
  9. Lee, S. Y., J. H. An, and H. Y. Cho. 2003. Isolation and characterization of MMP-1 inhibitor Peptide from Crataegus pinnatifida bunge in fibroblast cell line HS68 cells. J. Korean Soc. Agric. Chem. Biotechnol. 46, 60-65.
  10. Park, A. Y. 2009. Effects of Extracts from Chestnut Inner Shell on Skin Catholic University. Daegu, Korea.
  11. Seong, J. K. 2007. Lignan glycosides of vaccinium oldhami Miquel. Korean J. Pharmacognosy 38, 296-298.
  12. Suk, C. H. 1997. Pharmaceutical characteristics and dermatophysiological effects of cosmeceuticals containing Chestnut bark extracts. Chungang University. Seoul. Korea.
  13. Tsuji, N., S. Moriwaki, Y. Suzuki, Y. Takema, and G. Imokawa. 2001. The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity. Photochem. Photobiol. 74, 283-290. https://doi.org/10.1562/0031-8655(2001)074<0283:TROESB>2.0.CO;2
  14. Wunsch, E. and H. G. Heidrich. 1963. Zur quantitativen bestimmung der kollagenase. Hoppe-Seyler's. Physiol. Chem. 333. 149-151. https://doi.org/10.1515/bchm2.1963.333.1.149
  15. Yagi, A., T. Kanbara, and N. Morinobu. 1986. The effect of tyrosinase inhibition for aloe. Planta Medica. 3981, 517-519.
  16. Yang, M. J., S. J. Lim, H. S. Ahn, M. A. Kim, and R. M. Ahn. 1999. Inhibitory effect of Chestnut bark extracts on tyrosinase activity and melanin biosynthesis. Korean J. Env. Hlth Soc. 25, 37-43.
  17. Yoon, W. J. 1997. The study on the hemidity preserving effect with several natural packs, Dongduk womens University. Seoul, Korea.

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