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A Rare Case of Fat-Forming Variant of Solitary Fibrous Tumor Presenting as a Pleural Mass

  • Kim, Mi-Ae (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Lee, Ji-Hyun (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Jeong, Hye-Cheol (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Koo, Seung-Won (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Park, Kyung-Mi (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Cho, Sang-Ho (Department of Pathology, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Lee, Hyeon-Jae (Department of Thoracic and Cardiovascular Surgery, Bundang CHA Hospital, CHA University College of Medicine) ;
  • Kim, Eun-Kyung (Department of Internal Medicine, Bundang CHA Hospital, CHA University College of Medicine)
  • Received : 2011.08.22
  • Accepted : 2011.11.17
  • Published : 2011.06.30

Abstract

The fat-forming variant of solitary fibrous tumors (SFTs) is a rare soft tissue neoplasm that was previously referred to as a lipomatous hemangiopericytoma (L-HPC). The most common affected site is deep soft tissue. Here, we present the first case, worldwide, of a fat-forming variant of SFT of the pleura. A 74-year-old man presented with left lower chest pain. Chest radiographs showed a mass-like lesion at the left lower lung field and chest computed tomography revealed a 12 cm fat-containing enhancing mass that was well-separated, lobulated and inhomogeneous. Radiology findings suggested a liposarcoma. Percutaneous needle biopsy was performed and pathological diagnosis of the mass was a fat-forming variant of SFT. Surgical resection was carried out and there has been no recurrence to date. So, a benign fat-forming variant of SFT must be considered as one of the differential diagnoses of lipomatous tumors of the pleura.

Keywords

References

  1. Fletcher CD. The evolving classification of soft tissue tumours: an update based on the new WHO classification. Histopathology 2006;48:3-12. https://doi.org/10.1111/j.1365-2559.2005.02284.x
  2. Lee JR, Kim JS, Lee CH, Sohn KR. A case of lipomatous hemangiopericytoma of the nasal cavity. Korean J Otolaryngol-Head Neck Surg 2001;44:893-6.
  3. Kim MY, Rha SE, Oh SN, Lee YJ, Byun JY, Jung CK, et al. Case report. Lipomatous haemangiopericytoma (fat-forming solitary fibrous tumour) involving the perineum: CT and MRI findings and pathological correlation. Br J Radiol 2009;82:e23-6. https://doi.org/10.1259/bjr/26727658
  4. Nielsen GP, Dickersin GR, Provenzal JM, Rosenberg AE. Lipomatous hemangiopericytoma. A histologic, ultrastructural and immunohistochemical study of a unique variant of hemangiopericytoma. Am J Surg Pathol 1995;19:748-56. https://doi.org/10.1097/00000478-199507000-00002
  5. Liu X, Zhang HY, Bu H, Meng GZ, Zhang Z, Ke Q. Fat-forming variant of solitary fibrous tumor of the mediastinum. Chin Med J (Engl) 2007;120:1029-32.
  6. Guillou L, Gebhard S, Coindre JM. Lipomatous hemangiopericytoma: a fat-containing variant of solitary fibrous tumor? Clinicopathologic, immunohistochemical, and ultrastructural analysis of a series in favor of a unifying concept. Hum Pathol 2000;31:1108-15. https://doi.org/10.1053/hupa.2000.9777
  7. Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology 2006;48:63-74. https://doi.org/10.1111/j.1365-2559.2005.02290.x
  8. Cameselle-Teijeiro J, Manuel Lopes J, Villanueva JP, Gil-Gil P, Sobrinho-Simoes M. Lipomatous haemangiopericytoma (adipocytic variant of solitary fibrous tumour) of the thyroid. Histopathology 2003;43:406-8. https://doi.org/10.1046/j.1365-2559.2003.01696.x
  9. Pitchamuthu H, Gonzalez P, Kyle P, Roberts F. Fat-forming variant of solitary fibrous tumour of the orbit: the entity previously known as lipomatous haemangiopericytoma. Eye (Lond) 2009;23:1479-81.
  10. Robinson LA. Solitary fibrous tumor of the pleura. Cancer Control 2006;13:264-9.
  11. van de Rijn M, Lombard CM, Rouse RV. Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum, and lung. Am J Surg Pathol 1994;18:814-20. https://doi.org/10.1097/00000478-199408000-00008
  12. Theunissen PH, Ariens AT, Pannebakker MA, Blaauw G. Late recurrence of a hemangiopericytoma with lipomatous components. Pathologe 1990;11:346-9.
  13. Folpe AL, Devaney K, Weiss SW. Lipomatous hemangiopericytoma: a rare variant of hemangiopericytoma that may be confused with liposarcoma. Am J Surg Pathol 1999;23:1201-7. https://doi.org/10.1097/00000478-199910000-00004
  14. Ceballos KM, Munk PL, Masri BA, O'Connell JX. Lipomatous hemangiopericytoma: a morphologically distinct soft tissue tumor. Arch Pathol Lab Med 1999;123:941-5.
  15. Domanski HA. Fine-needle aspiration smears from lipomatous hemangiopericytoma need not be confused with myxoid liposarcoma. Diagn Cytopathol 2003;29:287-91 https://doi.org/10.1002/dc.10371