Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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Outcomes of Surgery for Dermatofibrosarcoma Protuberans and Risk Factor Analysis for Recurrence

융기성 피부섬유육종의 수술결과 및 재발의 위험 인자에 대한 분석

  • Lee, San-Ha (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Choi, Soon-Woo (View Plastic Surgery Clinic) ;
  • Jin, Ung-Sik (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Jeong, Eui-Cheol (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Minn, Kyung-Won (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine)
  • 이산하 (서울대학교 의과대학 성형외과학교실) ;
  • 최순우 (뷰 성형외과) ;
  • 진웅식 (서울대학교 의과대학 성형외과학교실) ;
  • 정의철 (서울대학교 의과대학 성형외과학교실) ;
  • 민경원 (서울대학교 의과대학 성형외과학교실)
  • Received : 2011.03.09
  • Accepted : 2011.07.28
  • Published : 2011.09.10
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Abstract

Purpose: Dermatofibrosarcoma protuberans is a relatively rare tumor that originates from the dermis and subcutaneous tissue. It is generally known that this tumor easily recurs but can be successfully treated with a wide excision. Therefore, this study was conducted to investigate postoperative outcomes and risk factors for recurrence in patients with dermatofibrosarcoma protuberans who were treated at a single institution for 20 years. Methods: We retrospectively reviewed the medical records of 35 patients who had underwent surgery between June 1992, and September 2010. The patients were assessed in terms of predilection site and size of the tumor, the incidence according to sex, discrepancy between biopsy results and histopathological diagnosis of the surgical specimen, additional treatment after recurrence, recurrence rate and the time interval to recurrence. Results: In multivariate analysis, the depth and site of the tumor were significant risk factors for tumor recurrence. The recurrence rate was significantly higher in tumors occurring in the upper extremity than those occurring in other regions ($p$=0.0348). In addition, the recurrence rate was significantly higher in tumors with involvement of the fascia and the deeper structures ($p$=0.0324, odds ratio=6, relative risk=1.588). Since dermatofibrosarcoma protuberans has strong invasiveness, its tissue involvement is difficult to evaluate accurately. Conclusion: The results of this study shows that involvement of the fascia and the deeper structures and occurrence in the upper extremity were associated with tumor recurrence. Therefore, clinicians should be aware of these risk factors to achieve better treatment outcomes.

Keywords

References

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