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Antioxidant and Antiatopic Effects of Refined Chaff Liquid Smoke

정제 왕겨초액의 항산화 및 항아토피 활성

  • Son, Hyeong-U (Department of Food Science & Technology, Food & Bio-Industry Research Institute, Kyungpook National University) ;
  • Heo, Jin-Chul (Department of Food Science & Technology, Food & Bio-Industry Research Institute, Kyungpook National University) ;
  • Kim, Suk-Kyung (Daewon GSI Co., Ltd.) ;
  • Kwon, Seon-Young (Daewon GSI Co., Ltd.) ;
  • Han, Gil-Hwan (Oriental Industry Supporting Center) ;
  • Lee, Sang-Han (Department of Food Science & Technology, Food & Bio-Industry Research Institute, Kyungpook National University)
  • 손형우 (경북대학교 식품공학과 및 식품생물산업연구소) ;
  • 허진철 (경북대학교 식품공학과 및 식품생물산업연구소) ;
  • 김숙경 (대원 GSI) ;
  • 권선영 (대원 GSI) ;
  • 한길환 (한방산업지원센터) ;
  • 이상한 (경북대학교 식품공학과 및 식품생물산업연구소)
  • Received : 2010.10.14
  • Accepted : 2011.02.18
  • Published : 2011.04.30

Abstract

The refined chaff liquid smoke purified by the second or third filtering, supplemented with Artemisia extract or Perillae folium extract was investigated by measuring antioxidant and antiatopic activities. In DPPH and FRAP assays, three kinds of chaff liquid smokes had potential in antioxidant activity. Additionally, we assessed for antiatopic activity by using C57BLl6 mice with stimulation of dinitrofluorobenzene and observed that their ear swelling was alleviated by various fractions. Overall, all of the chaff liquid smoke reduced the response of swelling on ear epidermis. Especially, refined chaff liquid smoke supplemented with Perillae folium extract was most active than any other fractions.

본 연구에서는 초액 4종인 2차 정제초액 (2nd refined liquid smoke, 2 CV), 3차 정제초액 (3'rd refined chaff liquid smoke, 3 CV), 쑥 정제초액(Artemisia plus refined chaff liquid smoke, A CV), 자소엽 정제초액 (Perillae folium plus refined chaff liquid smoke, Pf CV)의 항산화 능력과 항아토피 효과를 연구하였다. 항산화능 측정결과로 DPPH 활성은 3차 정제초액을 제외한 3종에서 높은 항산화 활성을 확인할 수 있었고, FRAP 실험 역시 DPPH와 마찬가지로 3종의 초액에서 높은 활성을 보였다. DNFB를 이용한 C57BL/6 마우스의 귀에 염증 유발을 통한 실험에서는 4가지 초액 모두 높은 활성을 보였다. 특히 육안, 귀의 두께 및 귀의 상피 두께를 확인한 결과 자소엽 초액이 염증을 유도한 군에 비해 두께가 현저히 감소하여 가장 높은 활성을 보였다.

Keywords

References

  1. Jeong CH, Shim KH (2002) Nitrite-scavenging and antioxdiant activities of wood vinegar. Korean J Food Preserv, 9, 351-355
  2. Kim SP, Nam SH (2009) Evalution and comparison of antioxidant activitys of nineteen commercial carbonated vinegar liquors. J. Appl Biol Chem, 52, 174-179 https://doi.org/10.3839/jabc.2009.030
  3. Lee FZ, Lee BD, Eun JB (2006) Antimicrobial activity and oxidative stability of bamboo smoke distillate on soybean oil during storage. Korean J Food Sci Tech, 38, 816-822
  4. Kim YH, Kim SK, Kim KS, Lee YH (2001) Composition of constituents of commercial wood vinegar liquor in Korea. J Korean Soc Agric Chem Biotechnol, 44, 262-268
  5. Kim YD, Bae ON, Chung SM, Chung JH (2004) Improvement of Haemostasis mediated by anti-platelet activities by plant vinegar. J Toxicol Public Health, 20, 137-142
  6. Park C, Choi YH, Lee WH, Choi BT, Lee YT, Kim GC (2003) Up-regulaton of bax and down-regulation of Bcl-2 in oak smoke flavoring(holyessing)-induced apoptosis of human prostate carcinoma cells. Korean J Oriental Physiology & Pathology, 17, 85-90
  7. Ryu HY, Heo JC, Hwang JS, Kang SW, Yun CY, Lee SH, Sohn HY (2008) Screening of thrombin inhibitor and its DPPH radical scavenging activity from wild insects. J Life Sci, 18, 363-368 https://doi.org/10.5352/JLS.2008.18.3.363
  8. Heo JC, Nam SH, Kang SW, Hong IP, Lee KK, Park JY, Kim KH, Han SY, Lee SH (2007) Comparison of antioxidant, anticancer and immunomodulating activities of extracts from DongChongXiaCao. Korean J Food Preserv, 14, 681-687
  9. Yanagisawa R, Takano H, Inoue K, Koike E, Sadakane K, Ichinose T (2008) Effects of maternal exposure to di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring. Environ Health Perspect, 116, 1136-1141 https://doi.org/10.1289/ehp.11191
  10. Rainsford KD (2005) The coxib controversies. Inflammopharmacology, 13, 331-341 https://doi.org/10.1163/156856005774415628
  11. ung IS, Kim YJ, Gal SW, Choi YJ (2007) Antimicrobial and antioxidant activities and inhibition of nitric oxide synthesis of oak wood vinegar. J Life Sci, 17, 105-109 https://doi.org/10.5352/JLS.2007.17.1.105
  12. Ikegami F, Sekine T, Fujii Y (1998) Anti-dermaptophyte activity of phenolic compounds in "mokusaku-eki". Yakugaku Zasshi, 118, 27-30
  13. Virk MS, Issenberg P (1986) Effects of phenol and 2,6-dimethyoxyphenol (syringol) on in vivo formation of N-nitrosomorpholine in rats. Carcinogenesis, 7, 867-870 https://doi.org/10.1093/carcin/7.6.867

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