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The Comparative Study on Decoctions of Yukmijihwang-tang (Liuweidihuang-tang) Extracted by Different Extraction Method and Extraction Time

전탕 방법 및 전탕 시간에 따른 육미지황탕 전탕액 비교 연구

  • Kim, Jung-Hoon (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Seo, Chang-Seob (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Jeon, Woo-Young (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Shin, Hyeun-Kyoo (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine)
  • 김정훈 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 서창섭 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 전우영 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 신현규 (한국한의학연구원 표준화연구본부 한약EBM연구센터)
  • Received : 2011.05.12
  • Accepted : 2011.06.13
  • Published : 2011.06.30

Abstract

Objectives : This study was performed to compare the differences between decoctions extracted by different extraction method and extraction time. Methods : Decoctions were prepared with pressed or non-pressed extraction conditions for 60, 120 and 180min. The yields of extracts, sugar contents, hydrogen ion concentrations(pH), the contents of reference compounds in Yukmijihwang-tang(Liuweidihuang-tang) were investigated. Results : The yields and the dissolved solid content containing sugar content of decoctions were more in pressed extraction method than unpressed extraction method, and they tended to be increased as extraction time increased. The pH values of decoctions methods did not show significant differences between pressed and unpressed extraction methods or extraction times. Most of reference compounds showed higher contents in pressed extraction method than unpressed extraction method and their contents were augmented according to increase of extraction time. The content of paeonol was decreased when extracted in more than 120min with pressed extraction method and tended to be decreased as extraction time increased in unpressed extraction method. Conclusions : The pressed extraction with long extraction time could be useful for decoction of Yukmijihwang-tang(Liuweidihuang-tang). However, another ingredients possible to decrease in such condition need to be considered to determine suitable extraction condition.

Keywords

References

  1. 한국한의학연구원. 2008년도 한방 의료 이용 실태조사. 서울:보건복지가족부. 2009:118.
  2. 김호철. 압력과 무압력 전탕의 차이. 꼭 알아야 할 한약이야기-6. 한의신문. 2010. Jul 30. Available from:URL:http://www.mjmedi.com/news/articleView,html?idxno=4182.
  3. 권영민. 한약 전탕방법 변해야 한다(3). 민족의학신문. 2004. Apr 19. Available from:URL:http://www.akomnews.co.kr/subpage/detail.php?code=B011&uid=57325&page
  4. 徐富一., 朴艺河, 金美麗, 壓方式과 無壓方式 煎湯方法으로 抽出한 五積散 물추출액이 關節炎에 미치는 效果. 동의경산 한의학 학술대회. 2000;4.
  5. 金度完, 朴昌國. 煎湯時間에 따른 生大黃 및 酒大黃이 瘀血病態模型에 미치는 影響. 大韓韓方內科學會誌. 1998;19(1):114-33.
  6. 李容範, 鞠潤範, 崔成模. Gas-Chromatography를 이용한 은교산 전탕시간에 대한 연구. 大韓韓醫學原典學會誌. 大韓韓醫學原典學會. 2006;19(1):202-6.
  7. 안규환, 최창민, 김송백, 조한백. 가미조경탕의 전탕 방법에 따른 항혈전 및 염증에 관한 연구. 대한한방부인과학회지. 2009;22(1):53-78.
  8. 김정훈, 서창섭, 신현규. 전탕 조건에 따른 쌍화탕 전탕액 비교 연구. 대한한의학 방제학회지. 2010;18(2):125-34.
  9. 이종태. 한국인의 한약재 복용실태 조사 연구. 서울:식품의약품안전청. 2006:91-4.
  10. 박요한, 황대선, 신현규. 한방의료기관 한약제제구비 현황 조사 연구. 대한한의학방제학회지. 2010;18(1):43-56.
  11. 程國彭. 醫學心悟. 文淵閣四唐全書. 서울:여강출판사. 1988:197.
  12. 吳壽金, 趙泰, 秦永祺 主編. 現代中草藥成分化學. 北京:中國医藥科枝術出版. 2002:635-6.
  13. 盧艷花. 中藥有效成分提取分离實例. 北京:化學工業出版社. 2007:138.