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The Comparative Study on Decoctions of Yukmijihwang-tang (Liuweidihuang-tang) Extracted by Different Extraction Method and Extraction Time

전탕 방법 및 전탕 시간에 따른 육미지황탕 전탕액 비교 연구

  • Kim, Jung-Hoon (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Seo, Chang-Seob (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Jeon, Woo-Young (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine) ;
  • Shin, Hyeun-Kyoo (Herbal Medicine EBM Research Center, Standard Research Division, Korea Institute of Oriental Medicine)
  • 김정훈 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 서창섭 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 전우영 (한국한의학연구원 표준화연구본부 한약EBM연구센터) ;
  • 신현규 (한국한의학연구원 표준화연구본부 한약EBM연구센터)
  • Received : 2011.05.12
  • Accepted : 2011.06.13
  • Published : 2011.06.30

Abstract

Objectives : This study was performed to compare the differences between decoctions extracted by different extraction method and extraction time. Methods : Decoctions were prepared with pressed or non-pressed extraction conditions for 60, 120 and 180min. The yields of extracts, sugar contents, hydrogen ion concentrations(pH), the contents of reference compounds in Yukmijihwang-tang(Liuweidihuang-tang) were investigated. Results : The yields and the dissolved solid content containing sugar content of decoctions were more in pressed extraction method than unpressed extraction method, and they tended to be increased as extraction time increased. The pH values of decoctions methods did not show significant differences between pressed and unpressed extraction methods or extraction times. Most of reference compounds showed higher contents in pressed extraction method than unpressed extraction method and their contents were augmented according to increase of extraction time. The content of paeonol was decreased when extracted in more than 120min with pressed extraction method and tended to be decreased as extraction time increased in unpressed extraction method. Conclusions : The pressed extraction with long extraction time could be useful for decoction of Yukmijihwang-tang(Liuweidihuang-tang). However, another ingredients possible to decrease in such condition need to be considered to determine suitable extraction condition.

Acknowledgement

Supported by : 한국한의학연구원

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